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首页> 外文期刊>Biology Bulletin >Biological Abilities and Identification of the Polyene Antifungal Antibiotic, Perspective for Protection from Fungi Biodeterioration
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Biological Abilities and Identification of the Polyene Antifungal Antibiotic, Perspective for Protection from Fungi Biodeterioration

机译：多烯抗真菌抗生素的生物学能力和鉴定，从真菌生物降解保护的角度来看。

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摘要

The producer of the antifungal polyene antibiotic, aimed to protect against fungial biodeterioration, has been isolated from the soil due to a target search. Based on the morphological, cultural, and biochemical abilities, the producer is related to the Streptomyces genus. It has been shown by chromatographic, spectral, physical, and chemical methods that the antibiotic synthesized by the isolated culture consists of two main components-the polyene hexaene antibiotic with a high antifungal activity and a non-polyene antibiotic with antibacterial activity. The antifungal activity of the low purified hexaene antibiotic is comparable with the antifungal activity of the well-known highly purified antibiotics-amphotericin B, clotrimazole, and itrakonazol. This antibiotic inhibits the synthesis of the biodeterioration factors in fungi, i.e., pigments and organic acids.
机译：由于目标搜索的缘故，已经从土壤中分离出了旨在防止真菌生物降解的抗真菌多烯抗生素生产商。根据形态，文化和生化能力，生产者与链霉菌属有关。通过色谱，光谱，物理和化学方法已经表明，分离培养物合成的抗生素包括两个主要成分：具有高抗真菌活性的多烯己烯抗生素和具有抗菌活性的非多烯抗生素。低纯度己烯抗生素的抗真菌活性可与众所周知的高纯度抗生素两性霉素B，克霉唑和依他那唑的抗真菌活性相媲美。这种抗生素抑制真菌中生物降解因子，即色素和有机酸的合成。

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  • 来源
    《Biology Bulletin》 |2010年第2期|p.193-202|共10页
  • 作者

    I. L. Kuzikova; V. I. Sukharevich; Yu. D. Shenin; N. G. Medvedeva;

  • 作者单位

    Scientific Research Center for Ecology, Russian Academy of Sciences, ul. Korpusnaya 18, St. Petersburg, 197110 Russia;

    Scientific Research Center for Ecology, Russian Academy of Sciences, ul. Korpusnaya 18, St. Petersburg, 197110 Russia;

    rnRussian Institute of Plants Protection, sh. Podbelskogo 3, St. Petersburg, Pushkin, 196608 Russia;

    rnScientific Research Center for Ecology, Russian Academy of Sciences, ul. Korpusnaya 18, St. Petersburg, 197110 Russia;

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