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首页> 外文期刊>Biology Bulletin >Correction of Changes Induced by Toluene in the Cortical and Subcortical Structures of Albino Rat Brain
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Correction of Changes Induced by Toluene in the Cortical and Subcortical Structures of Albino Rat Brain

机译：校正白化大鼠脑皮质和皮质下结构中甲苯诱导的变化

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摘要

The number and weight of cells in the cortical and subcortical structures of the cerebral and cere-bellar motor system in albino rats after a long-term exposure to toluene were determined. Toluene intoxication proved to kill projection neurons and interneurons in the sensorimotor cortex, ventrolateral thalamic nucleus, caudate nucleus, pallidum, red nucleus, and inferior olivary complex. The decreased number of cerebellar cells was mediated by atrophic changes as indicated by the decrease in the area and dry weight of Purkinje cells. The addition of plaferon LB to the diet attenuated the cytotoxic effect of toluene.
机译：确定了长期暴露于甲苯后，白化病大鼠大脑和小脑运动系统的皮质和皮质下结构的细胞数量和重量。甲苯中毒证明可杀死感觉运动皮层，腹外侧丘脑核，尾状核，苍白球，红色核和下橄榄核复合体中的投射神经元和中间神经元。小脑细胞数量的减少是由萎缩性改变介导的，如浦肯野细胞的面积和干重的减少所表明的。在饮食中添加普拉弗隆LB会减弱甲苯的细胞毒性作用。

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