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Neurocognitive therapeutics: from concept to application in the treatment of negative attention bias

机译:神经认知疗法:从概念到治疗负注意偏见的应用

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There is growing interest in the use of neuroimaging for the direct treatment of mental illness. Here, we present a new framework for such treatment, neurocognitive therapeutics. What distinguishes neurocognitive therapeutics from prior approaches is the use of precise brain-decoding techniques within a real-time feedback system, in order to adapt treatment online and tailor feedback to individuals’ needs. We report an initial feasibility study that uses this framework to alter negative attention bias in a small number of patients experiencing significant mood symptoms. The results are consistent with the promise of neurocognitive therapeutics to improve mood symptoms and alter brain networks mediating attentional control. Future work should focus on optimizing the approach, validating its effectiveness, and expanding the scope of targeted disorders.
机译:对神经影像直接治疗精神疾病的兴趣日益浓厚。在这里,我们提出了这种治疗的新框架,即神经认知疗法。神经认知疗法与现有方法的不同之处在于,在实时反馈系统中使用了精确的大脑解码技术,以便在线调整治疗方案并根据个人需求调整反馈。我们报告了一项初步的可行性研究,该研究使用该框架来改变少数患者出现严重的情绪症状时的负面注意偏见。结果与神经认知疗法有望改善情绪症状并改变介导注意力控制的大脑网络相一致。未来的工作应集中在优化方法,验证其有效性以及扩大目标疾病的范围上。

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