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首页> 外文期刊>World Journal of Gastroenterology >Two synchronous somatostatinomas of the duodenum and pancreatic head in one patient
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Two synchronous somatostatinomas of the duodenum and pancreatic head in one patient

机译：一名患者的十二指肠和胰头的两个同步性生长抑素瘤

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摘要

Somatostatinomas are extremely rare neuroendocrine tumors of the gastrointestinal tract, first described in the pancreas in 1977 and in the duodenum in 1979. They may be functional and cause somatostatinoma or inhibitory syndrome, but more frequently are non-functioning pancreatic endocrine tumors that produce somatostatin alone. They are usually single, malignant, large lesions, frequently associated with metastases, and generally with poor prognosis. We present the unique case of a 57-year-old woman with two synchronous non-functioning somatostatinomas, one solid duodenal lesion and one cystic lesion within the head of the pancreas, that were successfully resected with a pylorus-preserving Whipple's procedure. No secondaries were found in the liver, or in any of the removed regional lymph nodes. The patient had an uneventful recovery, and remains well and symptom-free at 18 mo postoperatively. This is an extremely rare case of a patient with two synchronous somatostatinomas of the duodenum and the pancreas. The condition is discussed with reference to the literature.
机译：生长抑素瘤是极为罕见的胃肠道神经内分泌肿瘤，于1977年在胰腺和1979年在十二指肠中首次发现。它们可能是功能性的并引起生长抑素瘤或抑制性综合征，但更常见的是无功能的胰腺内分泌肿瘤，其仅产生生长抑素。它们通常是单个的，恶性的，大的病变，经常与转移相关，并且通常预后较差。我们介绍了一个独特的案例，该例是一名57岁女性，患有两个同步无功能的生长抑素瘤，一个胰十二指肠实性病变和一个胰头内的囊性病变，并通过保留幽门的Whipple手术成功切除。在肝脏或任何已切除的区域淋巴结中均未发现次级。患者恢复良好，术后18个月仍无症状。这是患有十二指肠和胰腺的两个同步性生长抑素瘤的患者的极少数情况。该条件参考文献进行讨论。

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  • 来源
    《World Journal of Gastroenterology》 |2009年第46期|5859-5863|共5页
  • 作者

    Radoje B Colovic; Slavko V Matic; Marjan T Micev; Nikica M Grubor; Henry Dushan Atkinson; Stojan M Latincic;

  • 作者单位

    The First Surgical Clinic, Clinical Center of Serbia, Koste Todorovica 6, Belgrade 11000, Serbia;

    The First Surgical Clinic, Clinical Center of Serbia, Koste Todorovica 6, Belgrade 11000, Serbia;

    The First Surgical Clinic, Clinical Center of Serbia, Koste Todorovica 6, Belgrade 11000, Serbia;

    The First Surgical Clinic, Clinical Center of Serbia, Koste Todorovica 6, Belgrade 11000, Serbia;

    Surgical Directorate, Imperial College School of Medicine, St Mary's Hospital, Praed St, London W2 1 NY, United Kindom;

    The First Surgical Clinic, Clinical Center of Serbia, Koste Todorovica 6, Belgrade 11000, Serbia Clinical Center of Serbia, Institute for Digestive diseases, K. Todorovida 6 street, Belgrade 11000, Serbia;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    somatostatinoma; duodenal neoplasms; pancreatic neoplasms;

    机译：生长抑素瘤十二指肠肿瘤;胰腺肿瘤;

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