...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>World Journal of Gastroenterology >Comparison of long-term effects between intra-arterially delivered ethanol and Gelfoam for the treatment of severe arterioportal shunt in patients with hepatocellular carcinoma
【24h】

Comparison of long-term effects between intra-arterially delivered ethanol and Gelfoam for the treatment of severe arterioportal shunt in patients with hepatocellular carcinoma

机译：动脉内输送的乙醇和明胶泡沫对肝细胞癌患者重度门静脉分流的长期疗效比较

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

AIM: To evaluate long-term effect of ethanol embolization for the treatment of hepatocellular carcinoma (HCC) with severe hepatic arterioportal shunt (APS), compared with Gelfoam embolization. METHODS: Sixty-four patients (ethanol group) and 33 patients (Gelfoam group) with HCC and APS were respectively treated with ethanol and Gelfoam for APS before the routine interventional treatment for the tumor. Frequency of recanalization of shunt, complete occlusion of the shunt, side effects, complications, and survival rates were analyzed between the two groups. RESULTS: The occlusion rate of APS after initial treatment in ethanol group was 70.3%(45/64), and recanalization rate of 1 month after embolization was 17.8%(8/45), and complete occlusion rate was 82.8%(53/64). Those in Gelfoam group were 63.6%(21/33), 85.7%(18/21), and 18.2%(6/33). There were significant differences in recanalization rate and complete occlusion rate between the two groups (P<0.05). The survival rates in ethanol group were 78% at 6 months, 49% at 12 months, 25% at 24 months, whereas those in Gelfoam group were 58% at 6 months, 23% at 12 months, 15% at 24 months. The ethanol group showed significantly better survival than Gelfoam group (P<0.05). In the ethanol group, there was a significant prolongation of survival in patients with monofocal HCC (P<0.05) and Child class A (P<0.05). There were no significant differences in survival rate in the Gelfoam group with regard to the number of tumor and Child class (P>0.05). The incidence rate of abdominal pain during procedure in ethanol group was 82.8%. There was no significant difference in postembolization syndromes between two groups. Procedure-related hepatic failure did not occur in ethanol group. CONCLUSION: Ethanol embolization for patients with HCC and severe APS is efficacious and safe, and may contribute to prolongation of the life span versus Gelfoam embolization.
机译：目的：与Gelfoam栓塞术相比，评价乙醇栓塞术治疗重度肝动门分流（APS）治疗肝细胞癌（HCC）的长期效果。方法：在常规介入治疗之前，分别对64例（乙醇组）和33例（Gelfoam组）HCC和APS患者分别用乙醇和Gelfoam进行APS治疗。在两组之间分析了分流再通的频率，分流的完全闭塞，副作用，并发症和生存率。结果：乙醇组初次治疗后APS的闭塞率为70.3％（45/64），栓塞后1个月复通率为17.8％（8/45），完全闭塞率为82.8％（53/64）。 ）。 Gelfoam组的分别为63.6％（21/33），85.7％（18/21）和18.2％（6/33）。两组在再通率和完全阻塞率上有显着差异（P <0.05）。乙醇组的生存率在6个月时为78％，在12个月时为49％，在24个月时为25％，而Gelfoam组的生存率在6个月时为58％，在12个月时为23％，在24个月时为15％。乙醇组的生存率明显优于Gelfoam组（P <0.05）。在乙醇组中，单灶性肝癌（P <0.05）和儿童A级（P <0.05）的患者生存期显着延长。 Gelfoam组的存活率在肿瘤数目和儿童分类方面无显着差异（P> 0.05）。乙醇组手术过程中腹痛的发生率为82.8％。两组之间的栓塞后综合症无明显差异。乙醇组未发生与手术相关的肝衰竭。结论：对于肝癌和严重APS患者，乙醇栓塞术是有效且安全的，与Gelfoam栓塞术相比，可能有助于延长寿命。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号