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Factors predisposing to severe acute pancreatitis: evaluation and prevention

机译:导致严重急性胰腺炎的因素:评估和预防

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AIM: To analyze factors predisposing to the infections associated with severe acute pancreatitis (SAP) and to work out ways for its prevention. METHODS: Total 208 cases of SAP treated in this hospital from Jan. 1980 to Dec. 2001 were retrospectively analyzed. RESULTS: Statistical difference in the incidence of the aforementioned infections was found between the following pairs: between the groups of bloody or non-bloody ascites, paralytic ileus lasting shorter or longer than 5 days, Ranson scores lower or higher than 5, hematocrit lower or higher than 45 %, CT Balthazar scores lower or higher than 7 and between 1980.1-1992.6 or 1992.7-2001.12 admissions (x~2>3.84, P<0.05), while no statistical difference was established between the groups of biliogenic and non -biliogenic pancreatitis, serum amylase <200 U/L and ≥200 U/L, serum calcium <2 mmol /L and ≥ 2 mmol/L or groups of total parenteral nutrition shorter or longer than 7 days (x~2<3.84, P>0.05). CONCLUSION: Occurrence of infection in patients with SAP is closely related with bloody ascites, paralytic ileus ≥ 5 days, Ranson scores ≥5, hematocrit ≥45 % and CT Balthazar Scores ≥7, but not with pathogens, serum calcium and total parenteral nutrition (TPN). Comprehensive prevention of pancreatic infection and practice of individualized therapy contribute to reducing the incidence of infection.
机译:目的:分析导致严重急性胰腺炎(SAP)相关感染的因素,并找出预防方法。方法:回顾性分析该院1980年1月至2001年12月收治的208例SAP。结果:在以下几对之间发现上述感染发生率的统计差异:在血性或非血性腹水组之间,麻痹性肠梗阻持续时间短于或超过5天,兰森评分低于或高于5,血细胞比容低于或高于高于45%,CT Balthazar评分低于或高于7且在1980.1-1992.6或1992.7-2001.12入院之间(x〜2> 3.84,P <0.05),而胆源性和非胆源性两组之间无统计学差异胰腺炎,血清淀粉酶<200 U / L和≥200U / L,血清钙<2 mmol / L和≥2 mmol / L或总肠胃外营养组短于或长于7天(x〜2 <3.84,P> 0.05)。结论:SAP患者的感染发生与血性腹水,麻痹性肠梗阻≥5天,Ranson评分≥5,血细胞比容≥45%和CT Balthazar评分≥7有密切关系,但与病原体,血清钙和肠胃外总营养无关( TPN)。全面预防胰腺感染和实行个体化治疗有助于减少感染的发生。

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