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Acute Pancreatitis After Laparoscopic Transcystic Common Bile Duct Exploration: An Analysis of Predisposing Factors in 447 Patients

机译:腹腔镜转生殖常见胆管探测急性胰腺炎:447例患者易感因子分析

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Introduction In laparoscopic transcystic common bile duct exploration (LTCBDE), the risk of acute pancreatitis (AP) is well recognized. The present study assesses the incidence, risk factors, and clinical impact of AP in patients with choledocholithiasis treated with LTCBDE. Methods A retrospective database was completed including patients who underwent LTCBDE between 2007 and 2017. Univariate and multivariate analyses were performed by logistic regression. Results After exclusion criteria, 447 patients were identified. There were 70 patients (15.7%) who showed post-procedure hyperamylasemia, including 20 patients (4.5%) who developed post-LTCBDE AP. Of these, 19 were edematous and one was a necrotizing pancreatitis. Patients with post-LTCBDE AP were statistically more likely to have leukocytosis ( p ?
机译:在腹腔镜转生殖胆总管探测(LTCBDE)中引入,急性胰腺炎(AP)的风险得到了很好的认可。本研究评估AP在用LTCBDE治疗的胆干胆石病患者患者中的发病率,危险因素和临床影响。方法完成了回顾性数据库,包括在2007年至2017年期间进行LTCBDE的患者。单次数和多变量分析是通过物流回归进行的。结果在排除标准后,确定了447名患者。有70名患者(15.7%)显示出术后高亚亚血症,其中20名患者(4.5%)开发出LTCBDE AP。其中,19种是水肿,一个是坏死性的胰腺炎。患有后LTCBDE AP的患者在手术和较长的操作时间(OT,P?<0.001)之前,LTCBDE AP的患者更容易具有白细胞增多(P?<0.004)和黄疸(P?= 0.019);它们不太可能在偶然术中诊断(p?= 0.031)或将胆绞痛作为手术的原因(p?= 0.031)。在最终的多变量模型中,白细胞增多症(P?= 0.013)和OT(p?<0.001)仍有重要预测因子。平均术后医院住宿(HS)在AP组中明显更长(P?<?0.001)。结论AP的风险适度,应在术前白细胞增多和黄疸患者中考虑并暴露于较长的OT。 AP对术后HS产生强烈影响。

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