Effect of Maotai liquor in inducing metallothioneins and on hepatic stellate cells

Ming-Liang Cheng; Jun Wu; Hai-Qin Wang

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Effect of Maotai liquor in inducing metallothioneins and on hepatic stellate cells

机译：茅台酒诱导金属硫蛋白及对肝星状细胞的影响。

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CONCLUSION: Maotai liquor can increase metallothioneins in the liver and inhibit the activation of HSC and the synthesis of collagen in many aspects, which might be the mechanism that Maotai liquor interferes in the hepatic fibrosis. AIM: To explore the possible mechanism why drinking Maotai liquor dose not cause hepatic fibrosis. METHODS: After being fed with Maotai for 56 days consecutively, the male SD rats were decollated for detecting the biological indexes, and the livers were harvested to examine the liver indexes and the level of hepatic metallothioneins (MT). Hepatic stellate cells (HSC) proliferation and collagen generation were also observed.

机译：结论：茅台酒可以增加肝脏中金属硫蛋白的含量，并在许多方面抑制HSC的活化和胶原蛋白的合成，这可能是茅台酒干扰肝纤维化的机制。目的：探讨饮用茅台酒不引起肝纤维化的可能机制。方法：连续摄食茅台56天后，分离雄性SD大鼠以检测其生物学指标，并收集肝脏以检查肝脏指标和肝金属硫蛋白（MT）水平。还观察到肝星状细胞（HSC）增殖和胶原蛋白生成。

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《World Journal of Gastroenterology》 |2002年第3期|p.520-523|共4页
作者
Ming-Liang Cheng; Jun Wu; Hai-Qin Wang;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类消化系及腹部疾病;
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1. Differential effects between maotai and ethanol on hepatic gene expression in mice: Possible role of metallothionein and heme oxygenase-1 induction by maotai. [J] . Liu J, Cheng ML, Shi JZ, Experimental Biology and Medicine: Journal of the Society for Experimental Biology and Medicine . 2006,第9期

机译：茅台酒和乙醇对小鼠肝基因表达的不同影响：茅台金属硫蛋白和血红素加氧酶-1的可能作用。
2. Cadmium induces alpha(1)collagen (I) and metallothionein II gene and alters the antioxidant system in rat hepatic stellate cells. [J] . del Carmen EM, Souza V, Bucio L, Toxicology: An International Journal Concerned with the Effects of Chemicals on Living Systems . 2002,第1a2期

机译：镉诱导大鼠肝星状细胞中的α（1）胶原蛋白（I）和金属硫蛋白II基因，并改变抗氧化系统。
3. Apoptosis of hepatic stellate cells in carbon tetrachloride induced acute liver injury of the rat: analysis of isolated hepatic stellate cells. [J] . Lee JI, Lee KS, Paik YH, Journal of Hepatology: The Journal of the European Association for the Study of the Liver . 2003,第6期

机译：四氯化碳诱导的大鼠急性肝损伤中肝星状细胞的凋亡：分离的肝星状细胞的分析。
4. Flow and nitric oxide increase hepatic function in co-culturing hepatocytes with hepatic stellate cells and endothelial cells [C] . Sumii Tateki, Fujita Ryosuke, Tanishita Kazuo, 2011 International Symposium on Micro-NanoMechatronics and Human Science . 2011

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5. Exploring the mechanism of cannabidiol-induced death of activated hepatic stellate cells. [D] . Lim, Maribel P. 2011

机译：探索大麻素诱导的活化肝星状细胞死亡的机制。
6. Effect of Maotai liquor in inducing metallothioneins and on hepatic stellate cells [O] . Ming-Liang Cheng, Jun Wu, Hai-Qin Wang, 2002

机译：茅台酒诱导金属硫蛋白及对肝星状细胞的影响。
7. Cell cycle protein profile of the hepatic stellate cells (HSCs) in dimethylnitrosamine-induced rat hepatic fibrosis [O] . Mi-Rhan Kim, Han-Seong Kim, Mi Sook Lee, 2005

机译：肝星状细胞（HSC）在二甲基硝氰胺诱导的大鼠肝纤维化中的细胞周期蛋白谱

Effect of Maotai liquor in inducing metallothioneins and on hepatic stellate cells

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