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首页> 外文期刊>World Journal of Gastroenterology >Coinfection of TT virus and response to interferon therapy in patients with chronic hepatitis B or C
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Coinfection of TT virus and response to interferon therapy in patients with chronic hepatitis B or C

机译：慢性乙型或丙型肝炎患者TT病毒的共感染和对干扰素治疗的反应

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CONCLUSION: TTV is not infrequently coinfected in patients with chronic hepatitis B and C in Taiwan, and more than half of the TTV infections are IFN-sensitive. However, the loss of serum TTV DNA does not affect the clinical course of the patients with chronic hepatitis B or C. AIM- To investigate the serum positive percentage of TT virus (TTV) in patients with chronic hepatitis B or C and the response of the coinfected TFV to interferon (IFN) during IFN therapy for chronic hepatitis B and C. METHODS: We retrospectively studied the serum samples of 70 patients with chronic hepatitis who had received IFN-alfa therapy from January 1997 to June 2000, which included 40 cases of hepatitis B and 30 hepatitis C. All the patients had been followed up for at least 6 months after the end of IFN therapy. The serum TFV DNA was detected using the polymerase chain reaction (PCR) before and every month during the course of IFN treatment.
机译：结论：在台湾的慢性乙型和丙型肝炎患者中，TTV很少并发感染，并且一半以上的TTV感染对IFN敏感。但是，血清TTV DNA的丢失不会影响慢性乙型或丙型肝炎患者的临床病程。目的-研究慢性乙型或丙型肝炎患者的TT病毒（TTV）血清阳性百分比以及对乙型肝炎的反应方法：回顾性研究了1997年1月至2000年6月接受IFN-α治疗的70例慢性肝炎患者的血清样本，其中包括40例病例。分别接受了乙型肝炎和30例丙型肝炎治疗。所有患者均在IFN治疗结束后接受了至少6个月的随访。在IFN治疗之前和期间，使用聚合酶链反应（PCR）检测血清TFV DNA。

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