• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Chemosphere >Pilot study to assess effects of collection tube types and processing delay on measurements of persistent organic pollutants and lipids in human serum
【24h】

Pilot study to assess effects of collection tube types and processing delay on measurements of persistent organic pollutants and lipids in human serum

机译：评估收集管类型和处理延迟对人体血清中持久性有机污染物和脂质测量的影响的试验研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Glass red top tubes (RTs), traditionally used to draw blood for biomonitoring studies, have some limitations during field sampling (e.g., tube breakage, timely processing may be difficult). This pilot study examined whether serum separation tubes (SSTs) with delayed processing time (48 h) can be used instead of red top tubes (RTs) to accommodate field conditions. Using state-of-the-art methodologies, PBDEs, PCBs, OCPs, PFCs, cholesterol and triglycerides were measured to evaluate any differences among 2 test conditions (RTs with 2 h processing time; SSTs with 48 h processing time). Between the 2 test conditions, we observed high rank correlations among the measured compounds and no statistically significant differences in the levels of measured compounds. We conclude that SSTs with delayed processing time (48 h) produce similar results as RTs with short processing time (2 h), suggesting that SSTs could be good substitutes for RTs for new epidemiological and biomonitoring field studies. The use of SSTs offers a tremendous opportunity for the use of samples archived in various SSTs.
机译：玻璃红顶管（RTs）传统上是用来抽取血液进行生物监测研究的，在野外采样期间存在一些局限性（例如，管子破裂，可能难以及时处理）。这项初步研究检查了是否可以使用具有延迟处理时间（48小时）的血清分离管（SST）代替红顶管（RT）来适应现场条件。使用最先进的方法，对多溴二苯醚，多氯联苯，OCP，PFC，胆固醇和甘油三酸酯进行了测量，以评估2种测试条件（处理时间为2小时的RT；处理时间为48小时的SST）之间的差异。在这两种测试条件之间，我们观察到了所测化合物之间的高度相关性，并且所测化合物的水平没有统计学上的显着差异。我们得出结论，延迟处理时间（48小时）的SST产生的结果与处理时间短（2小时）的RT产生的结果相似，这表明SST可以很好地替代RT，用于新的流行病学和生物监测现场研究。 SST的使用为使用各种SST中存档的样本提供了巨大的机会。

著录项

  • 来源
    《Chemosphere》 |2014年第12期|75-82|共8页
  • 作者

    W. Guo; D. Nelson; S. Hurley; P. Reynolds; T. Guo; M. Wang; J.-S. Park; M. Petreas;

  • 作者单位

    California Department of Toxic Substances Control, 700 Heinz Ave., Berkeley, CA 94710, USA;

    Cancer Prevention Institute of California, Berkeley, CA 94704, USA;

    Cancer Prevention Institute of California, Berkeley, CA 94704, USA;

    Cancer Prevention Institute of California, Berkeley, CA 94704, USA;

    California Department of Toxic Substances Control, 700 Heinz Ave., Berkeley, CA 94710, USA,Sequoia Foundation, La Jolla, CA 92037, USA;

    California Department of Toxic Substances Control, 700 Heinz Ave., Berkeley, CA 94710, USA;

    California Department of Toxic Substances Control, 700 Heinz Ave., Berkeley, CA 94710, USA;

    California Department of Toxic Substances Control, 700 Heinz Ave., Berkeley, CA 94710, USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Polychlorinated biphenyls (PCBs); Polybrominated diphenyl ethers (PBDEs); Organochlorine pesticides (OCPs); Perfluorinated compounds (PFCs); Serum Separation Tubes (SSTs); Red top tubes (RTs);

    机译：多氯联苯（PCB）;多溴二苯醚（PBDEs）;有机氯农药（OCPs）;全氟化合物（PFC）;血清分离管（SST）;红顶管（RTs）;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号