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Prospective memory in schizophrenia and schizotypy

机译：精神分裂症和精神分裂症的前瞻性记忆

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Introduction. Most evidence suggests that schizophrenia is associated with pervasive prospective memory (PM) impairment that does not vary as a function of task demands. However, a central tenet of the Multiprocess Framework is that PM involves both automatic and strategic processes, and that their relative prominence varies as a function of PM task characteristics, such as target-cue saliency. Methods. Participants with schizophrenia (n=30), matched controls (n=29), low schizotypes (n=35), and high schizotypes (n=36) were administered a PM measure in which saliency was manipulated. To further clarify the relationship between PM and schizotypy, high and low schizotypies were additionally assessed on Virtual Week, a laboratory measure which has documented sensitivity to schizophrenia-related impairment. Results Relative to controls, participants with schizophrenia exhibited PM difficulties, but the magnitude of this deficit did not vary as a function of target-cue saliency. High and low schizotypes did not differ on any PM test parameter. Conclusions These data are consistent with other evidence showing that schizophrenia is characterised by generalised PM impairment. However, the absence of any schizotypy effects on PM does not support the recent suggestion that PM may represent an endophenotype for schizophrenia.View full textDownload full textKeywordsCue detection, Neurocognition, Prospective memory, Schizophrenia, SchizotypyRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/13546805.2011.581536
机译：介绍。大多数证据表明，精神分裂症与普遍的前瞻性记忆（PM）损伤有关，后者不会随任务需求而变化。但是，多进程框架的中心原则是PM涉及自动和战略流程，并且它们的相对重要性随PM任务特征（例如目标提示显着性）的变化而变化。方法。对患有精神分裂症（n = 30），匹配的对照（n = 29），低精神分裂症型（n = 35）和高精神分裂症型（n = 36）的参与者进行PM措施，在其中操纵显着性。为了进一步阐明PM与精神分裂症之间的关系，还在虚拟周上对高和低的精神分裂症进行了评估，这是一项实验室措施，已证明对精神分裂症相关损伤的敏感性。结果相对于对照，精神分裂症患者表现出PM困难，但是这种缺陷的程度并未随目标提示显着性的变化而变化。高和低分型在任何PM测试参数上均无差异。结论这些数据与其他证据表明精神分裂症的特征在于广泛性PM损害相一致。然而，对PM缺乏任何精神分裂症的影响并不支持最近的建议，即PM可能代表精神分裂症的内表型。在线”，services_compact：“ citeulike，netvibes，twitter，technorati，可口，linkedin，facebook，stumbleupon，digg，google，更多”，发布号：“ ra-4dff56cd6bb1830b”};添加到候选列表链接永久链接http://dx.doi.org/10.1080/13546805.2011.581536

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