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Sexual dimorphism of spatial working memory profiles in schizophrenia

机译：精神分裂症患者空间工作记忆特征的两性性

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Introduction. The aim of the present study was to compare spatial working memory performance of females and males schizophrenia patients to verify whether the sexual dimorphism of spatial abilities present in the general population is found also in schizophrenia. Methods. We analysed different types of errors committed by each gender on the spatial working memory test of the Cambridge Neuropsychological Test Automated Battery to determine potential differences between them. Results. Despite the lack of difference in the number of errors between men and women, different profiles of errors were associated with the strategy used according to gender. The men's strategy was better compared to women. Specifically, for women strategy score correlated positively with searches in previously visited boxes, whereas for men it correlated with both previously visited boxes and never visited ones. However, men's strategy is more impaired by the number of revisits in boxes in which tokens have previously been found than female's one. Conclusions. These results suggested impaired either central executive and/or visuospatial sketchpad of working memory in patients with schizophrenia. We demonstrated also that the worsening of strategy in men is principally due to central executive deficits compared to women with schizophrenia. The study of sex differences in cognitive performances could help in delineating partially different endophenotypes of schizophrenia in men and women.View full textDownload full textKeywordsEndophenotype, Gender, Schizophrenia, Sexual dimorphism, Working memoryRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/13546800903399183
机译：介绍。本研究的目的是比较女性和男性精神分裂症患者的空间工作记忆表现，以验证是否在精神分裂症中也发现了普通人群中存在的空间能力的性别二态性。方法。我们在剑桥神经心理学测试自动电池的空间工作记忆测试中分析了每种性别所犯的不同类型的错误，以确定它们之间的潜在差异。结果。尽管男女之间的错误数量没有差异，但根据性别所采用的策略与错误的类型有关。与女性相比，男性的策略更好。具体而言，对于女性，策略得分与以前访问过的盒子中的搜索呈正相关，而对于男性，它与既往访问过的盒子以及从未访问过的盒子相关。但是，男人的策略受以前发现代币的盒子中重新访问的次数比女性的影响更大。结论。这些结果表明，精神分裂症患者的中央执行力和/或视觉空间画板的工作记忆受损。我们还证明，与患有精神分裂症的女性相比，男性的策略恶化主要是由于中央执行力不足。对认知表现的性别差异进行研究有助于区分男性和女性精神分裂症的部分内异表型。查看全文下载全文关键词services_compact：“ citeulike，netvibes，twitter，technorati，可口，linkedin，facebook，stumbleupon，digg，google，更多”，发布：“ ra-4dff56cd6bb1830b”};添加到候选列表链接永久链接http://dx.doi.org/10.1080/13546800903399183

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