• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Computer speech and language >Verbal fluency in normal aging and cognitive decline: Results of a longitudinal study
【24h】

Verbal fluency in normal aging and cognitive decline: Results of a longitudinal study

机译：言语流畅性在正常老龄化和认知下降：纵向研究的结果

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Verbal fluency - i.e. the ability to name as many words of a given category as possible in a defined time interval - is an integral part of neuropsychological test batteries for the diagnosis of dementia. Verbal fluency can be easily administered and thus may also be implemented in computerized dementia screening tests. In the present study we sought to investigate the capability of phonemic verbal fluency as a potential predictor of cognitive decline and its associations with acoustic and lexical features directly inferred from recordings of spoken language. Data from 246 ILSE participants born in the years 1930 to 1932 were included. Subjects were investigated three times (t1-t3) over a period of more than 10 years by two board certified geriatric psychiatrists: the mean age of the sample was 62.77 at t1, 66.36 at t2, and 74.22 at t3. To evaluate the sensitivity of phonemic fluency performance on cognitive impairment, scores obtained at tl and t2 were compared with repeated measures ANOVA between subjects who were cognitively intact and those who were diagnosed with mild cognitive impairment (MCI) or Alzheimer's dementia (AD) at t3. In addition, acoustic and lexical features of spoken language were extracted with automatic speech recognition from semi-structured autobiographical interviews recorded at baseline. Scores were correlated with verbal fluency performance at tl. In all analyzes education was considered as a covariate. Regarding verbal fluency obtained at tl and t2, repeated measures ANOVA revealed significantly higher scores between subjects who were cognitively intact (HC) at t3 compared with those diagnosed with MCI or AD at t3. At baseline verbal fluency was significantly correlated with important acoustic features of spontaneous speech: word rate, phoneme rate, speech-duration and silence-to-word-ratio. Verbal fluency deficits were proven already in young old age and precede marked cognitive decline years before in a large group recruited from the general population. Verbal fluency is associated with acoustic rather than lexical features of spoken language which can directly be inferred from spontaneous speech.
机译：言语流畅 - 即在规定的时间间隔中将给定类别的许多单词命名的能力是神经心理学测试电池的组成部分，用于诊断痴呆症。可以容易地施用口头流畅性，因此也可以在计算机化痴呆筛查测试中实现。在本研究中，我们试图调查音素言语流畅性的能力作为认知下降的潜在预测因子及其与声学和词汇特征的关联，直接从口语录音中推断出来。包括在1930年至1932年出生的246名ILSE参与者的数据。通过两个董事会认证的老年精神病学家（T3，T2的T1,66.36的平均年龄为62.77，在T3，T3时的平均年龄为62.77，在T3，T3的平均年龄为62.77）。为了评估对认知障碍的敏感性流畅性能的敏感性，将T1和T2获得的分数与被认知完整的受试者之间的反复测量和诊断为轻度认知障碍（MCI）或Alzheimer的痴呆（AD）的疗法之间的分数进行比较。此外，通过在基线记录的半结构化自传式访谈中提取语言的声学和词法特征。评分与TL的口头流畅性能相关。在所有分析中，教育被视为一个协变量。关于在T1和T2获得的言语流畅性，反复测量Anova在与在T3诊断的人的患有MCI或AD的人相比，在T3的受试者之间显示出显着更高的评分。在基线口语流畅性与自发语音的重要声学特征显着相关：词汇率，音素率，语音持续时间和沉默与字词。在年轻的年龄上已经证明了言语流畅性缺陷，并在从一般人群中招募的大型团体之前明显的认知衰退。言语流畅性与声学而不是语言的词汇特征有关，可以直接从自发的语音推断出来。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号