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Upconversion nanoprobes for biodetections

机译：上转换纳米探针用于生物检测

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摘要

Lanthanide-doped upconversion nanomaterials that convert low energy excitation wavelength to high energy emission have attracted considerable attention due to the advantages of high penetration depth and high resistance to autofluorescence interference capability. This review highlights the literature of the past several years covering recent advances of upconversion nanoprobes for biodetection. We begin by discussions of the key points in fabrication of lanthanide-activated nanoprobes. We further conduct a careful evaluation of various detection applications of upconversion nanoprobes, including temperature, ions, small molecules, DNA, enzyme, virus, and etc. We finish the discussion by assessing current challenges and future prospects of upconversion nanoprobes for fundamental studies and clinical applications. (C) 2017 Elsevier B.V. All rights reserved.
机译：由于具有高穿透深度和高抗自发荧光干扰能力的优点，将低能量激发波长转换为高能量发射的掺杂镧系元素的上转换纳米材料引起了相当大的关注。这篇综述重点介绍了过去几年的文献，这些文献涵盖了用于生物检测的上转换纳米探针的最新进展。我们首先讨论镧系元素激活的纳米探针制造中的关键点。我们进一步仔细评估了上转换纳米探针的各种检测应用，包括温度，离子，小分子，DNA，酶，病毒等。我们通过评估上转换纳米探针在基础研究和临床上的当前挑战和未来前景来结束讨论应用程序。 （C）2017 Elsevier B.V.保留所有权利。

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  • 来源
    《Coordination chemistry reviews》 |2018年第1期|155-168|共14页
  • 作者

    Li Zhenhua; Yuan Hang; Yuan Wei; Su Qianqian; Li Fuyou;

  • 作者单位

    Fudan Univ, Dept Chem, State Key Lab Mol Engn Polymers, 220 Handan Rd, Shanghai 200433, Peoples R China|Fudan Univ, Inst Biomed Sci, 220 Handan Rd, Shanghai 200433, Peoples R China;

    Fudan Univ, Dept Chem, State Key Lab Mol Engn Polymers, 220 Handan Rd, Shanghai 200433, Peoples R China|Fudan Univ, Inst Biomed Sci, 220 Handan Rd, Shanghai 200433, Peoples R China;

    Fudan Univ, Dept Chem, State Key Lab Mol Engn Polymers, 220 Handan Rd, Shanghai 200433, Peoples R China|Fudan Univ, Inst Biomed Sci, 220 Handan Rd, Shanghai 200433, Peoples R China;

    Fudan Univ, Dept Chem, State Key Lab Mol Engn Polymers, 220 Handan Rd, Shanghai 200433, Peoples R China|Fudan Univ, Inst Biomed Sci, 220 Handan Rd, Shanghai 200433, Peoples R China|Shanghai Univ, Inst Nanochem & Nanobiol, Shangda Rd, Shanghai 200444, Peoples R China;

    Fudan Univ, Dept Chem, State Key Lab Mol Engn Polymers, 220 Handan Rd, Shanghai 200433, Peoples R China|Fudan Univ, Inst Biomed Sci, 220 Handan Rd, Shanghai 200433, Peoples R China;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Upconversion nanoparticles; Detections; Lanthanide; Energy transfer;

    机译：上转换纳米粒子;检测;镧系元素;能量转移;

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