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首页> 外文期刊>Bali Medical Journal >Correlation between verruca vulgaris and superoxide dismutase
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Correlation between verruca vulgaris and superoxide dismutase

机译：寻常疣与超氧化物歧化酶的相关性

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Background : Verruca vulgaris is a form of benign tumors that infected epidermal cells caused by Human papillomavirus (HPV). In several studies states that imbalances in oxidant and antioxidant systems play an important role in HPV infection. SOD is a potent protective enzyme that selectively cleanses radicals of antioxidants by catalyzing dismutation to hydrogen peroxide. Aim : The study aimed to determine the correlation between SOD level and verruca vulgaris . Method s : This was an analytic study with a cross sectional design involving 35 subjects with verruca vulgaris and 35 healthy controls. Diagnosis of verruca vulgaris was made based on history and clinical examination. The authors conducted blood sampling and measurement of plasma SOD level to the patients and controls. Results: The study found that the mean of SOD levels in verruca vulgaris patients were higher (49.27 ± 100.47 U/L) than controls (35.12 ± 50.44 U/L), but it didn’t find a correlation between verruca vulgaris and SOD with p = 0.511. The mean level of ≥ 6 months were higher (59.69 ± 140.85 U/L) than < 6 months (39.43 ± 36.09 U/L) with p = 0.369. The mean multiple lesion levels were higher (62.12 ± 140.76 U/L) than the SOD level of patients with a single lesion (37.14 ± 34.89 U/L) with p = 0.405. The mean of SOD levels of patients who had previously experienced verruca vulgaris was higher (72.79 ± 151.73 U/L) than those who had not it (31.63 ± 18.26 U/L) with p = 0.961. Conclusion : We didn’t found a correlation between verruca vulgaris and SOD.
机译：背景：寻常疣（Verruca vulgaris）是一种良性肿瘤，感染了由人乳头瘤病毒（HPV）引起的表皮细胞。在一些研究中指出，氧化剂和抗氧化剂系统的失衡在HPV感染中起重要作用。 SOD是一种有效的保护酶，可通过催化歧化为过氧化氢来选择性清除抗氧化剂的自由基。目的：研究旨在确定SOD水平与寻常疣之间的相关性。方法：这是一项分析研究，采用横断面设计，涉及35名寻常疣患者和35名健康对照。根据病史和临床检查对寻常疣进行诊断。作者对患者和对照组进行了血液采样和血浆SOD水平的测量。结果：研究发现寻常型疣状患者的SOD水平平均值（49.27±100.47 U / L）高于对照组（35.12±50.44 U / L），但未发现寻常型疣状与SOD呈正相关。 p ＝ 0.511。 ≥6个月的平均水平（59.69±140.85 U / L）高于<6个月（39.43±36.09 U / L），p = 0.369。多发病变平均水平（62.12±140.76 U / L）高于单一病变患者的SOD水平（37.14±34.89 U / L），p = 0.405。以前患有寻常疣的患者的SOD水平平均值（72.79±151.73 U / L）高于不患有寻常疣的患者（31.63±18.26 U / L），p = 0.961。结论：我们没有发现寻常疣和SOD之间存在相关性。

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