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Anti-Diuretic Impact of Aerva Lanata Extracts and their Active Compounds in Furosemide Administered Diuretic Rats

机译:Aerva Lanata提取物及其活性化合物对呋塞米利尿大鼠的抗利尿作用

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Bioactive compounds of aromatic and medicinal plants showed remarkable activity against bacteria and fungi. Medicinal plants were used to inhibit the pathogens and cure most of the diseases like diuretics, diabetics etc., Hence, in the present study the antidiuretic activity of the Aerva lanata was analysed and discussed. In this study, total urine output in normal animals was 1.32 ± 0.22 ml/kg of animal per day, but diuretic animal had 1.76 ± 0.26 ml/kg/day. It was increased to 44% and stimulated the action of diuretic 1.5 fold in this study. Furosemide (Standard diuretic drug) induced percentage secretion of saline was 8.52 ± 0.56 and urine excretion was 7.38 ± 0.53. The active compound of Aerva lanata was showed to reduce the remarkable and reach the control value and showed antidiuretic efficiency. Total urine output in diuretic induced animal treated with 2-Decyl -1-tetra decanol was 1.30 ± 0.27 ml/kg of animal per day compared to control (1.32 ± 0.22 ml/kg of animal per day) it was decreased 2% and stimulated the action of diuretic 1 fold. The active compound of A. lanata, 2-Decyl -1-tetra decanol induced percentage of secretion of saline was 8.76 ± 0.52 and urine excretion was 7.49 ± 0.48. The standard antidiuretic hormone also showed similar value of active compounds of Aerva lanata. From the investigations the Aerva lanata is to be used effective cheap plant based drug for diuretic diseases.
机译:芳香和药用植物的生物活性化合物显示出显着的抗细菌和真菌活性。药用植物被用来抑制病原体并治愈大多数疾病,如利尿剂,糖尿病等。因此,在本研究中,对Aerva lanata的抗利尿活性进行了分析和讨论。在这项研究中,正常动物的总尿量为每天1.32±0.22 ml / kg动物,而利尿动物为1.76±0.26 ml / kg / day。在这项研究中,它增加到44%,并刺激利尿剂作用1.5倍。速尿(标准利尿药)诱导的生理盐水分泌百分比为8.52±0.56,尿液排泄为7.38±0.53。结果表明,苍术有效成分降低显着性并达到对照值,并具有利尿作用。用2-癸基-1-四癸醇处理的利尿剂诱导动物的总尿量为每天1.30±0.27 ml / kg动物,而对照组(1.32±0.22 ml / kg动物每天)减少2%并刺激利尿作用1倍。桔梗的活性化合物2-癸基-1-四癸醇诱导的盐水分泌百分比为8.76±0.52,尿液排泄为7.49±0.48。标准的抗利尿激素也显示了苍术活性成分的相似价值。从调查结果看,Aerva lanata将被用作有效的廉价植物性利尿剂药物。

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