• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Ophthalmology >Health state utilities in patients with diabetic retinopathy, diabetic macular oedema and age-related macular degeneration: a systematic review
【24h】

Health state utilities in patients with diabetic retinopathy, diabetic macular oedema and age-related macular degeneration: a systematic review

机译：糖尿病性视网膜病变，糖尿病性黄斑水肿和年龄相关性黄斑变性患者的健康状况实用程序：系统评价

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Health state utility values (HSUVs) are important in the assessment of the cost effectiveness of new interventions. In the case of visual conditions, models generally tend have tended to be built around a set of health states defined by visual acuity (VA). The aim of this review was to assess the impact of VA on HSUVs in patients with diabetic retinopathy, diabetic macular oedema or age-related macular degeneration. Methods A systematic literature search was undertaken in major bibliographic databases to identify articles reporting on the relationship between HSUVs and vision. Data were extracted for population characteristics, visual levels and estimated utilities. Evidence from reported statistical models, where available, was considered in the evaluation of vision in the better-seeing eye and the worse-seeing eye. Due to the heterogeneity of included studies, a narrative synthesis was undertaken. Results Of the 17 relevant studies, 9 studies had data that could be used in the analysis of the impact of vision on HSUVs. Visual loss was associated with a marked impact on health utilities. However, the relationship was not comparable between conditions or by measure of HSUVs. Key results included the finding that overall, self-rated time-trade off estimates were more likely to discriminate between different VA levels than EQ-5D values. Additionally, a stronger correlation was observed between HSUVs and better-seeing eye VA compared to worse-seeing eye VA. Conclusions Visual acuity has a significant impact on HSUVs. Nevertheless, care must be taken in the interpretation and use of estimates in cost-effectiveness models due to differences in measures and population diversity.
机译：背景健康状态效用值（HSUV）在评估新干预措施的成本效益方面很重要。在视觉状况下，通常倾向于围绕由视敏度（VA）定义的一组健康状态建立模型。这篇综述的目的是评估VA对糖尿病性视网膜病变，糖尿病性黄斑水肿或年龄相关性黄斑变性的HSUVs的影响。方法在主要的书目数据库中进行系统的文献检索，以鉴定报道HSUV和视觉之间关系的文章。提取了有关人口特征，视觉水平和估计效用的数据。在评估视力较好和较差的眼睛的视力时，会考虑使用已报告的统计模型提供的证据。由于纳入研究的异质性，因此进行了叙述性综合。结果在17项相关研究中，有9项研究的数据可用于分析视觉对HSUV的影响。视力丧失与对卫生事业的显着影响有关。但是，这种关系在条件之间或按HSUV的量度上是不可比较的。关键结果包括发现，与EQ-5D值相比，总的，自我评估的时间权衡估计更可能区分不同的VA水平。此外，相比于视力较差的眼睛VA，HSUV与视力较好的VA之间具有更强的相关性。结论视敏度对HSUV有重要影响。但是，由于措施和人口多样性的差异，在成本效益模型中对估计的解释和使用必须谨慎。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号