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首页> 外文期刊>BMC research notes >Assessing clustering of metabolic syndrome components available at primary care for Bantu Africans using factor analysis in the general population
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Assessing clustering of metabolic syndrome components available at primary care for Bantu Africans using factor analysis in the general population

机译：使用总人口中的因子分析评估班图非洲人在初级保健中可获得的代谢综合征成分的聚类

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Background To provide a step-by-step description of the application of factor analysis and interpretation of the results based on anthropometric parameters(body mass index or BMI and waist circumferenceor WC), blood pressure(BP), lipid-lipoprotein(triglycerides and HDL-C) and glucose among Bantu Africans with different numbers and cutoffs of components of metabolic syndrome(MS). Methods This study was a cross-sectional, comparative, and correlational survey conducted between January and April 2005, in Kinshasa Hinterland, DRC. The clustering of cardiovascular risk factors was defined in all, MS group according to IDF(WC, BP, triglycerides, HDL-C, glucose), absence and presence of cardiometabolic risk(CDM) group(BMI,WC, BP, fasting glucose, and post-load glucose). Results Out of 977 participants, 17.4%( n?=?170), 11%( n?=?107), and 7.7%(n?=?75) had type 2 diabetes mellitus(T2DM), MS, and CDM, respectively. Gender did not influence on all variables. Except BMI, levels of the rest variables were significantly higher in presence of T2DM than non-diabetics. There was a negative correlation between glucose types and BP in absence of CDM. In factor analysis for all, BP(factor 1) and triglycerides-HDL(factor 2) explained 55.4% of the total variance. In factor analysis for MS group, triglycerides-HDL-C(factor 1), BP(factor 2), and abdominal obesity-dysglycemia(factor 3) explained 75.1% of the total variance. In absence of CDM, glucose (factor 1) and obesity(factor 2) explained 48.1% of the total variance. In presence of CDM, 3 factors (factor 1?=?glucose, factor 2?=?BP, and factor 3?=?obesity) explained 73.4% of the total variance. Conclusion The MS pathogenesis may be more glucose-centered than abdominal obesity-centered in not considering lipid-lipoprotein , while BP and triglycerides-HDL-C could be the most strong predictors of MS in the general population. It should be specifically defined by ethnic cut-offs of waist circumference among Bantu Africans.
机译：背景技术根据人体测量学参数（体重指数或BMI和腰围或WC），血压（BP），脂质-脂蛋白（甘油三酸酯和HDL），对因子分析的应用进行逐步描述并解释结果-C）和具有不同数量和不同代谢综合征成分截断值的非洲班图人之间的葡萄糖。方法本研究是2005年1月至2005年4月在刚果民主共和国金沙萨腹地进行的横断面，比较性和相关性调查。在所有MS组中，根据IDF（WC，BP，甘油三酸酯，HDL-C，葡萄糖），是否存在心脏代谢风险（CDM）组（BMI，WC，BP，空腹血糖，和加载葡萄糖后）。结果在977名参与者中，有2型糖尿病（T2DM），MS和CDM占17.4％（n？=？170），11％（n？=？107）和7.7％（n？=？75），分别。性别并未影响所有变量。除BMI外，存在T2DM时其余变量的水平显着高于非糖尿病患者。在没有CDM的情况下，葡萄糖类型与BP之间呈负相关。在所有因子分析中，BP（因子1）和甘油三酸酯-HDL（因子2）解释了总方差的55.4％。在MS组的因素分析中，甘油三酸酯-HDL-C（因素1），BP（因素2）和腹部肥胖-血糖异常（因素3）解释了总方差的75.1％。在没有CDM的情况下，葡萄糖（因子1）和肥胖症（因子2）解释了总变异的48.1％。在存在CDM的情况下，3个因素（因素1α=β葡萄糖，因素2α=βBP，因素3α=β肥胖）解释了总方差的73.4％。结论在不考虑脂质-脂蛋白的情况下，MS的发病机制可能以葡萄糖为中心，而不是以腹部肥胖为中心，而BP和甘油三酸酯-HDL-C可能是一般人群中MS的最强预测因子。应该通过班图族非洲人的腰围种族界限来具体定义。

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