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首页> 外文期刊>Brazilian Journal of Cardiovascular Surgery >Elevated plasma D-dimer and hypersensitive C-reactive protein levels may indicate aortic disorders
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Elevated plasma D-dimer and hypersensitive C-reactive protein levels may indicate aortic disorders

机译：血浆D-二聚体和超敏C反应蛋白水平升高可能表明主动脉疾病

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OBJECTIVE: D-dimer and C-reactive protein are of diagnostic and predictive values in patients have thrombotic tendency, such as vascular thrombosis, coronary artery disease and aortic dissection. However, the comparative study in these biomarkers between the patients with acute aortic dissection and coronary artery disease has not been sufficiently elucidated. METHODS: Consecutive surgical patients for acute type A aortic dissection (20 patients), aortic aneurysm (nine patients) or coronary artery disease (20 patients) were selected into this study. Plasma from preoperative blood samples and supernatant of aortic homogenate of the surgical specimens were detected for D-dimer and hypersensitive C-reactive protein (hs-CRP). RESULTS: Plasma D-dimer and hs-CRP values in type A aortic dissection or aortic aneurysm were much higher than in coronary artery disease patients or the healthy control (for D-dimer, aortic dissection: coronary artery disease, 0.4344 ± 0.2958 μg/ml vs. 0.0512 ± 0.0845 μg/ml, P
机译：目的：D-二聚体和C反应蛋白对具有血栓形成趋势的患者具有诊断和预测价值，例如血管血栓形成，冠状动脉疾病和主动脉夹层。然而，尚未充分阐明急性主动脉夹层和冠心病患者之间在这些生物标志物中的比较研究。方法：本研究选择了急性A型主动脉夹层连续手术患者（20例），主动脉瘤（9例）或冠状动脉疾病（20例）。检测术前血样中的血浆和手术标本的主动脉匀浆上清液中的D-二聚体和超敏C反应蛋白（hs-CRP）。结果：A型主动脉夹层或主动脉瘤中的血浆D-二聚体和hs-CRP值远高于冠状动脉疾病患者或健康对照组（对于D-二聚体，主动脉夹层：冠状动脉疾病，0.4344±0.2958μg/毫升vs.0.0512±0.0845μg/ ml，P

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