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Antimicrobial Activity of Isothiocyanates (ITCs) Extracted from Horseradish (Armoracia rusticana) Root against Oral Microorganisms

机译:辣根提取物异硫氰酸盐(ITCs)对口腔微生物的抗菌活性

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The antimicrobial activity of isothiocyanates (ITCs) extracted from horseradish root was investigated against oral microorganisms: 6 strains of facultative anaerobic bacteria, Streptococcus mutans, Streptococcus sobrinus, Lactobacillus casei, Staphylococcus aureus, Enterococcus faecalis and Aggregatibacter actinomycetemcomitans ; one strain of yeast, Candida albicans , and 3 strains of anaerobic bacteria, Fusobacterium nucleatum, Prevotella nigrescens , and Clostridium perfringens . The ITCs extracted from horseradish root showed antimicrobial activity against all oral microorganisms by the paper disk method. The minimum bactericidal concentration (MBC) of the ITCs extracted from horseradish root ranged from 1.25 to 5.00 mg/ml against 6 strains of facultative anaerobic bacteria and one strain of yeast, and 4.17 to 16.67 mg/ml against 3 strains of anaerobic bacteria. The ITCs extracted from horseradish root showed the strongest antimicrobial activity, with a MBC of 1.25 mg/ml, against C. albicans among facultative microorganisms, and 4.17 mg/ml against F. nucleatum among anaerobic bacteria. These results suggest that the ITCs extracted from horseradish root may be a candidate for use as an antimicrobial agent against oral microorganisms.
机译:研究了从辣根中提取的异硫氰酸盐(ITCs)对口腔微生物的抗菌活性:6株兼性厌氧菌,变形链球菌,链球菌,干酪乳杆菌,金黄色葡萄球菌,粪肠球菌和聚合酶放线菌; 1株酵母为白色念珠菌,3株厌氧菌为核融合杆菌,黑短杆菌和产气荚膜梭状芽胞杆菌。通过纸盘法从辣根中提取的ITC对所有口腔微生物均具有抗菌活性。辣根提取物对6株兼性厌氧菌和1株酵母菌的ITC的最低杀菌浓度(MBC)为1.25至5.00 mg / ml,对3株厌氧菌的ITC的最低杀菌浓度为4.17至16.67 mg / ml。从辣根中提取的ITC对IC表现出最强的抗菌活性,MBC为1.25 mg / ml。兼性微生物中的白色念珠菌,抗F的浓度为4.17 mg / ml。厌氧菌之间的核。这些结果表明,从辣根中提取的ITC可能是用作口腔微生物抗菌剂的候选药物。

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