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首页> 外文期刊>BMC Psychiatry >Evaluation of a school-based depression prevention program among adolescents with elevated depressive symptoms: study protocol of a randomized controlled trial
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Evaluation of a school-based depression prevention program among adolescents with elevated depressive symptoms: study protocol of a randomized controlled trial

机译：在抑郁症高发青少年中基于学校的抑郁症预防计划的评估：一项随机对照试验的研究方案

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Background Adolescents are at risk of developing depressive symptoms. Given the prevalence, recurrence and negative consequences of adolescent depression, it is crucial to implement prevention programs for high-risk adolescents. Prevention programs at an indicated level have shown to be successful in reducing depressive symptoms in adolescents. This study will evaluate the (cost)effectiveness of the prevention program ‘Op Volle Kracht (OVK 2.0)’ for adolescents with elevated depressive symptoms. Methods We will perform a Randomized Controlled Trial (RCT) with an intervention and control condition to test the effectiveness of an indicated prevention program aimed at depression in adolescents. Adolescents in their second year of secondary education (11–15 year) will be screened for depressive symptoms. Those with heightened levels of depressive symptoms (CDI-2?≥?14) will be randomly assigned to the intervention ( N =?80) or control group ( N =?80). The participants in the intervention condition will receive a prevention program comprising eight meetings of 60?min each. The participants in the control condition will receive psycho-educational information. All participants and their parents will complete assessment at baseline, post-intervention, and 6-, 12- and 24- month follow-up. Primary outcome will be depressive symptoms. Additionally, the present study will identify mechanisms that mediate and moderate the program effects and test the effect of OVK 2.0 on secondary outcomes. Discussion This paper describes a study designed to screen adolescents for depressive symptoms and offer them a prevention program to prevent the onset of depressive symptomatology. Adolescents in the intervention condition are expected to show lower levels of depressive symptoms at 12?month follow-up compared to adolescents in the control condition. If OVK 2.0 proves to be effective, the screening and intervention program could be implemented in schools on a large scale. Trial registration Dutch Trial Register NTR5725 . Date registered: 11th of March 2016.
机译：背景青少年有发展为抑郁症状的风险。考虑到青春期抑郁症的患病率，复发率和负面后果，对高危青少年实施预防计划至关重要。在一定水平上的预防计划已显示出成功地减轻了青少年的抑郁症状。这项研究将评估预防方案“ Op Volle Kracht（OVK 2.0）”对抑郁症状加重的青少年的（成本）效果。方法我们将在干预和控制条件下进行随机对照试验（RCT），以测试针对青少年抑郁症的明确预防计划的有效性。将对处于中学第二年（11-15岁）的青少年进行抑郁症状筛查。抑郁症状加重（CDI-2≥≥14）的患者将被随机分配至干预组（N =≥80）或对照组（N =≥80）。干预条件下的参与者将接受一项预防计划，其中包括八次每次60分钟的会议。控制条件下的参与者将收到心理教育信息。所有参与者及其父母将在基线，干预后以及6、12和24个月的随访中完成评估。主要结果将是抑郁症状。此外，本研究将确定介导和调节程序效果的机制，并测试OVK 2.0对次要结果的影响。讨论本文描述了一项旨在筛查青少年抑郁症状的研究，并为他们提供了预防抑郁症状发作的预防方案。与对照组相比，干预条件下的青少年预期在12个月的随访中表现出较低的抑郁症状水平。如果证明OVK 2.0有效，则可以在学校中大规模实施筛查和干预计划。试用注册荷兰试用注册NTR5725。注册日期：2016年3月11日。

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