Occult Breast Carcinoma Presenting With Anti-Ri-Associated Paraneoplastic Cerebellar Degeneration Revealed With FDG-PET

Aziz Bazine; Mohamed Fetohi; Maha Ait Berri; Yacir Oufroukhi; Mohamed Ichou; Hassan Errihani

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Occult Breast Carcinoma Presenting With Anti-Ri-Associated Paraneoplastic Cerebellar Degeneration Revealed With FDG-PET

机译：FDG-PET显示隐匿性乳腺癌与抗Ri相关的副肿瘤小脑变性

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Paraneoplastic neurological syndromes are rare diseases affecting less than 0,01 % of the cancerous patients. Here, we present a rare case of paraneoplastic cerebellar degeneration with anti-Ri antibodies as the presenting manifestation of an occult breast cancer. Our observation emphasizes the importance of the nature of the anti-neuronal antibody and the fluorodeoxyglucose-positron emission tomography to make a definitive diagnosis in patients with subactue onset of neurological deficit suggesting paraneoplastic cerebellar degeneration.

机译：副肿瘤神经综合症是罕见的疾病，影响不到0.01％的癌症患者。在这里，我们提出了罕见的病例，伴有抗Ri抗体的副肿瘤性小脑变性是隐匿性乳腺癌的表现。我们的观察结果强调了抗神经元抗体和氟脱氧葡萄糖-正电子发射断层扫描的性质对做出提示神经系统缺陷亚型的副反应性小脑变性的患者做出明确诊断的重要性。

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《Cancer and Clinical Oncology》 |2014年第1期|共32页
作者
Aziz Bazine; Mohamed Fetohi; Maha Ait Berri; Yacir Oufroukhi; Mohamed Ichou; Hassan Errihani;
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1. Anti-Ri-associated paraneoplastic cerebellar degeneration and breast cancer: an autopsy case study. [J] . Brieva-Ruiz L, Diaz-Hurtado M, Matias-Guiu X, Clinical neurology and neurosurgery . 2008,第10期

机译：抗Ri相关性副肿瘤小脑变性和乳腺癌：尸检案例研究。
2. Anti-Ri-associated paraneoplastic cerebellar degeneration. Report of a case and revision of the literature [J] . Mancuso M., Orsucci D., Bacci A., Archives Italiennes de Biologie . 2011,第3期

机译：抗Ri相关性副肿瘤小脑变性。病例报告和文献修订
3. Anti-Ri-associated paraneoplastic brainstem cerebellar syndrome with coexisting limbic encephalitis in a patient with mixed large cell neuroendocrine lung carcinoma [J] . Mitchell Amber N., Bakhos Charles T., Zimmerman Earl A. Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia . 2015,第2期

机译：混合性大细胞神经内分泌肺癌患者的抗Ri相关性副肿瘤性脑干小脑综合征并存的边缘性脑炎
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机译：乳腺MRI的基于深度学习的特征可预测导管癌的隐匿性浸润性疾病：初步数据
5. CDR2 protein expression in the mouse cerebellum and a potential model of paraneoplastic cerebellar degeneration [D] . Harding, Emily Amanda 2009

机译：小鼠小脑中的CDR2蛋白表达和副肿瘤性小脑变性的潜在模型
6. Paraneoplastic cerebellar degeneration as a manifestation of metastatic recurrent carcinoma breast: rare scenario [O] . Shivangi Saha, Atish Kumar, Chitresh Kumar, 2018

机译：平原小脑退化作为转移性复发性癌乳房的表现：罕见的情景
7. Hodgkin lymphoma-associated paraneoplastic cerebellar degeneration on FDG-PET/CT [O] . Olivier Gheysens, Christophe M. Deroose, Thomas Tousseyn, 2013

机译：霍奇金淋巴瘤相关的肺状榫骨细胞变性FDG-PET / CT

Occult Breast Carcinoma Presenting With Anti-Ri-Associated Paraneoplastic Cerebellar Degeneration Revealed With FDG-PET

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