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首页> 外文期刊>Case Reports in Critical Care >Ketamine Infusion Associated with Improved Neurology in a Patient with NMDA Receptor Encephalitis
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Ketamine Infusion Associated with Improved Neurology in a Patient with NMDA Receptor Encephalitis

机译：氯胺酮输注与NMDA受体脑炎患者的神经功能改善相关

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A young lady was ventilated on intensive care for a prolonged period with NMDA receptor encephalitis. She had undergone steroid, immunoglobulin, and plasmapheresis with no evidence of recovery. Her main management issue was the control of severe orofacial and limb dyskinesia. Large doses of sedating agents had been used to control the dystonia but were ineffective, unless she was fully anaesthetised. The introduction of a ketamine infusion was associated with a dramatic improvement in her symptoms such that it was possible to remove her tracheostomy two days after commencement. She was discharged shortly after that and is making a good recovery. The successful use of ketamine has not previously been described in this context, and we hope this case report will provide some insight into the management of this rare but serious condition.
机译：一位年轻女士因重症监护而长期接受NMDA受体脑炎通气。她曾接受过类固醇，免疫球蛋白和血浆置换，无任何康复迹象。她的主要管理问题是控制严重的口腔颌面和肢体运动障碍。大剂量镇静剂已用于控制肌张力障碍，但除非完全麻醉，否则无效。氯胺酮输注的引入显着改善了她的症状，因此有可能在开始两天后切除气管切开术。此后不久，她已出院，并且恢复良好。氯胺酮的成功使用尚未在此背景下进行过描述，我们希望本病例报告能为这种罕见但严重的疾病的治疗提供一些见识。

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