Interstitial pneumonitis associated with pegylated interferon-alpha 2a and ribavirin for chronic hepatitis C infection: a case report

Ozlen Atug; Hakan Akin; Yesim Ozen Alahdab; Berrin Ceyhan; Nurdan Tozun; Osman Ozdogan

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Interstitial pneumonitis associated with pegylated interferon-alpha 2a and ribavirin for chronic hepatitis C infection: a case report

机译：聚乙二醇干扰素-α2a和利巴韦林联合治疗慢性丙型肝炎的间质性肺炎：病例报告

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Interstitial pneumonitis is a rare but potentially fatal side effect occurring from 2 weeks to 16 weeks after the initiation of treatment with pegylated interferon alpha and ribavirin for chronic hepatitis C. Herein, we present a 68-year-old man with chronic hepatitis C virus infection who developed interstitial pneumonitis association with pegylated interferon after 36 weeks initiation of pegylated interferon-alpha and ribavirin therapy. He did not recover after discontinuation of pegylated interferon/ribavirin and improved by steroid therapy.

机译：间质性肺炎是一种罕见的但可能致命的副作用，发生于开始使用聚乙二醇化干扰素α和利巴韦林治疗慢性丙型肝炎后的2周至16周。在此，我们介绍了一名68岁的慢性丙型肝炎病毒感染者在开始使用聚乙二醇化干扰素-α和利巴韦林治疗36周后，与聚乙二醇化干扰素发生了间质性肺炎。停用聚乙二醇化干扰素/利巴韦林后，他没有恢复，并通过类固醇疗法得以改善。

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《Cases Journal》 |2009年第1期|共页
作者
Ozlen Atug; Hakan Akin; Yesim Ozen Alahdab; Berrin Ceyhan; Nurdan Tozun; Osman Ozdogan;
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1. Comparision of the Side Effects Due To Interferon Alpha 2A Plus Ribavirin and Pegylated Interferon Alpha 2A Plus Ribavirin Combinations For Chronic Hepatitis C Infection [J] . Onur URAL, Nazl?m AKTU? DEM?R, ?ua SüMER, Trakya Universitesi. Tip Fakultesi Dergisi. . 2010,第3期

机译：干扰素α2A加利巴韦林和聚乙二醇化干扰素α2A加利巴韦林联合治疗慢性丙型肝炎的副作用比较
2. Amino acid sequence analysis in patients with chronic HCV genotype 1b infection during pegylated interferon-alpha 2a and ribavirin therapy [J] . Fu Juan-Juan, Kong Wei-Jing, Jiang Dong, Antiviral therapy . 2014,第7期

机译：聚乙二醇干扰素-α2a和利巴韦林治疗期间慢性HCV基因型1b感染患者的氨基酸序列分析
3. Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-alpha and ribavirin combination therapy in patients with chronic hepatitis C virus infection. [J] . Tatsumi T, Takehara T, Miyagi T, Hepatology research: the official journal of the Japan Society of Hepatology . 2011,第1期

机译：慢性丙型肝炎病毒感染患者中，丙型肝炎病毒特异的CD8 + T细胞频率与聚乙二醇化干扰素-α和利巴韦林联合治疗的反应有关。
4. Studies of Therapy with Thymosin α 1 in Combination with Pegylated Interferon α2a and Ribavirin in Nonresponder Patients with Chronic Hepatitis C [C] . ROBERTO CAMERINI, ALESSIA CIANCIO, ALFONSO DE ROSA, International Symposiumn on Thymosins in Health and Disease; 20070321-24; Washington,DC(US) . 2007

机译：胸腺素α1联合聚乙二醇化干扰素α2a和利巴韦林治疗慢性丙型肝炎无反应者的研究
5. The meaning of adherence among veterans receiving pegylated interferon and ribavirin antiviral treatment for chronic hepatitis C. [D] . Phillips, Frances Hinshaw. 2011

机译：接受聚乙二醇干扰素和利巴韦林抗病毒治疗的慢性丙型肝炎退伍军人依从性的含义。
6. Interstitial pneumonitis associated with pegylated interferon-alpha 2a and ribavirin for chronic hepatitis C infection: a case report [O] . Ozlen Atug, Hakan Akin, Yesim Ozen Alahdab, 2009

机译：聚乙二醇干扰素-α2a和利巴韦林联合治疗慢性丙型肝炎的间质性肺炎：病例报告
7. Interstitial pneumonitis associated with pegylated interferon-alpha 2a and ribavirin for chronic hepatitis C infection: a case report [O] . 2009

机译：聚乙二醇干扰素-α2a和利巴韦林联合治疗慢性丙型肝炎的间质性肺炎：病例报告

Interstitial pneumonitis associated with pegylated interferon-alpha 2a and ribavirin for chronic hepatitis C infection: a case report

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