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首页> 外文期刊>Bangladesh Journal of Medical Science >Correlation of Lipoprotein (a) Level with Complexity of Coronary Lesion in Coronary Heart Disease Patient at RSUP Dr. Sardjito Yogyakarta
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Correlation of Lipoprotein (a) Level with Complexity of Coronary Lesion in Coronary Heart Disease Patient at RSUP Dr. Sardjito Yogyakarta

机译：RSUP冠心病患者脂蛋白（a）水平与冠状动脉病变复杂度的关系Sardjito Yogyakarta博士

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Background: In 2020 there were estimated to be 25 million deaths each year from cardiovascular disease; most of them being coronary heart disease. Traditional risk factors such as smoking, hypertension, diabetes, dyslipidemia reported to affect only 50% of the prevalence and degree of coronary heart disease. It pushes a lot of research on non-traditional risk factors one of which is lipoprotein (a). Levels of Lp (a) also reflects the degree of severity and is associated with the number of coronary arteries involved. The purpose of this study was to determine the relationship of Lp (a) level with the complexity of coronary artery lesion.Methods: This was a cross-sectional study. Subjects were male and women patients aged between 20 to 60 years who underwent coronary angiography?for theirs STEMI, NSTEMI, unstable angina pectoris, and stable angina pectoris. Correlation between elevated Lp (a) with the complexity of coronary artery lesion was performed by Pearson test. If the distribution was abnormal we used Spearman test.Result: Number of samples was 64 subjects (49 men and 15 women). The result showed a significant positive correlation between Lp (a) level and complexity of coronary vessel lesion that counted by SYNTAX score (p 0,004) even though the coefficient correlation is weak (r 0, 33).Conclusion: The higher Lp (a) level shows bigger SYNTAX score which means the coronary vessel lesion more complex.Bangladesh Journal of Medical Science Vol.15(3) 2016 p.362-367
机译：背景：到2020年，每年估计有2500万人死于心血管疾病。他们大多数是冠心病。据报道，吸烟，高血压，糖尿病，血脂异常等传统危险因素仅影响冠心病患病率和程度的50％。它推动了许多关于非传统危险因素的研究，其中之一是脂蛋白（a）。 Lp（a）的水平也反映了严重程度，并与所涉及的冠状动脉数量有关。这项研究的目的是确定Lp（a）水平与冠状动脉病变的复杂性之间的关系。方法：这是一项横断面研究。受试者为年龄在20至60岁之间的男性和女性患者，因其STEMI，NSTEMI，不稳定型心绞痛和稳定型心绞痛而接受了冠状动脉造影。 Lp（a）升高与冠状动脉病变复杂程度之间的相关性通过Pearson检验进行。如果分布异常，则使用Spearman检验。结果：样本数量为64位受试者（男性49位，女性15位）。结果显示，尽管系数相关性较弱（r 0，33），但SYNTAX评分（p 0,004）计算出的Lp（a）水平与冠状动脉病变复杂度之间存在显着正相关。结论：Lp（a）越高水平显示出更大的SYNTAX评分，这意味着冠状动脉病变更加复杂。孟加拉国医学杂志Vol.15（3）2016 p.362-367

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