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Effect of Solvents on the Surface Modification of Hydrophilic Macro-Porous Particles with an Ion-Exchange Monomer Having Both Anion and Cation Exchange Groups

机译:含阴离子和阳离子交换基团的离子交换单体对亲水性大孔颗粒表面改性的影响

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摘要

An ion-exchange monomer including an anion exchange group and a cation exchange group, 2-methacryloyloxyethyl- phosphoryl choline (MPC) was introduced on the surface of uniformly sized, hydrophilic macro-porous polymer particle. We carefully studied several solvents utilized for the surface modification to elucidate solubility of the monomer as well as its polymer into each solvent. Based on the change in existing form of poly-MPC modified on the surface of stationary phases, ion-exchange properties of poly-MPC were controllable to result in interesting selectivity changes in HPLC.
机译:将包含阴离子交换基团和阳离子交换基团的离子交换单体2-甲基丙烯酰氧基乙基-磷酰胆碱(MPC)引入尺寸均一的亲水性大孔聚合物颗粒的表面。我们仔细研究了几种用于表面改性的溶剂,以阐明单体及其聚合物在每种溶剂中的溶解度。基于固定相表面改性的聚-MPC的现有形式的变化,可以控制聚-MPC的离子交换性能,从而在HPLC中产生有趣的选择性变化。

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