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首页> 外文期刊>Circulation journal >Gender Differences in the Clinical Characteristics and Outcomes of Patients With Vasospastic Angina – A Report From the Japanese Coronary Spasm Association –
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Gender Differences in the Clinical Characteristics and Outcomes of Patients With Vasospastic Angina – A Report From the Japanese Coronary Spasm Association –

机译：血管痉挛性心绞痛患者临床特征和结果的性别差异–来自日本冠状动脉痉挛协会的报告–

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Background: ?Accumulating evidence has demonstrated the gender differences in the clinical characteristics and outcomes of patients with ischemic heart disease. However, it remains to be elucidated whether it is also the case for vasospastic angina (VSA). Methods and Results: ?We enrolled a total of 1,429 VSA patients (male/female, 1090/339; median age 66 years) in our nationwide multicenter registry by the Japanese Coronary Spasm Association. As compared with male patients, female patients were characterized by older age (median 69 vs. 66 years), lower incidence of smoking (20% vs. 72%) and less significant organic stenosis (9% vs. 16%) (all P=0.001). Multivariate analysis demonstrated that the predictors of major adverse cardiac events (MACE) were considerably different by genders; women were more associated with age and electrical abnormalities, whereas men with structural abnormalities. Overall 5-year MACE-free survival was comparable between both genders. However, when the patients were divided into 3 groups by age [young (
机译：背景：越来越多的证据表明，缺血性心脏病患者的临床特征和结局存在性别差异。但是，是否还有血管痉挛性心绞痛（VSA）也有待阐明。方法和结果：？我们在日本冠脉痉挛协会的全国多中心登记处共纳入1,429例VSA患者（男性/女性，1090/339;中位年龄66岁）。与男性患者相比，女性患者的特征是年龄较大（中位年龄为69岁对66岁），吸烟率较低（20％对72％）和明显器质性狭窄（9％对16％）（所有P = 0.001）。多变量分析表明，主要不良心脏事件（MACE）的预测因子在性别上有很大差异。女性与年龄和电气异常有关，而男性与结构异常有关。男女的5年无MACE总生存期相当。但是，按年龄将患者分为3组[年轻（

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