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首页> 外文期刊>Case Reports in Obstetrics and Gynecology >Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality
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Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality

机译：妊娠合并脉络膜血管瘤和胎盘间质发育异常：罕见的胎盘异常。

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Background. Pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia (PMD) coexisting with a normal viable fetus is very rare. The literature was reviewed to explore the incidence and genetic origin of this condition.Case. The case was first identified by prenatal ultrasonography, but the prenatal diagnosis only included chorioangioma. PMD was then confirmed during postnatal evaluation, which included gross and histologic examination of the placenta. The macroscopic and microscopic findings were consistent with concomitant chorioangioma and placental mesenchymal dysplasia during pregnancy. Genetic findings confirmed genetic similarity of the chorioangioma and vesicle-like villi with the fetus.Conclusions. The case represents a rare placental abnormality whose pathogenesis and molecular basis need further research. Detailed histologic and genetic analyses are essential for accurate and differential diagnosis.
机译：背景。伴有正常绒毛的胎儿并发绒毛膜血管瘤和胎盘间质发育不良（PMD）的情况非常罕见。文献进行了审查，以探讨这种情况的发生率和遗传起源。该病例首先通过产前超声检查确定，但产前诊断仅包括绒毛膜血管瘤。然后在产后评估中确认PMD，包括胎盘的肉眼检查和组织学检查。宏观和微观检查结果与妊娠期合并绒毛膜血管瘤和胎盘间质发育异常相符。遗传学发现证实绒毛膜血管瘤和囊样绒毛与胎儿的遗传相似性。该病例代表罕见的胎盘异常，其发病机理和分子基础需要进一步研究。详细的组织学和遗传学分析对于准确和鉴别诊断至关重要。

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