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Bone cement distribution in the vertebral body affects chances of recompression after percutaneous vertebroplasty treatment in elderly patients with osteoporotic vertebral compression fractures

机译:老年骨质疏松性椎体压缩性骨折患者的经皮椎体成形术治疗后,椎体内骨水泥的分布会影响再压缩的机会

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Objective: Percutaneous vertebroplasty (PVP) is a surgical procedure that has been widely used to treat patients suffering from osteoporotic vertebral compression fractures (OVCFs). The procedure involves injection of bone cement into a fractured vertebra. In this study, we investigated whether the distribution of the cement in the vertebral body is related to the occurrence of recompression after surgery. Patients and methods: A total of 172 patients diagnosed with OVCF, from January 2008 to June 2013, were retrospectively reviewed. Fifty of these patients experienced recompression after surgery during the follow-up period (recompression group), and 122 patients had no recompression observed during the follow-up period (control group). Statistical analysis was performed to compare clinical and operative parameters between these two groups. Results: Differences were found in bone cement distribution between the recompression group and control group ( P =0.001). Patients with bone cement distributed around both upper and lower endplates had a significantly less incidence of recompression (4/50 patients), when compared to other patterns of cement distribution (eg, below upper endplate, above lower endplate, and in the middle of vertebral body). The logistic multiple regression analysis also indicated that patients with bone cement distributed around both the upper and lower endplates had a lower risk of recompression when compared to patients with bone cement distributed in the middle of vertebral body (odds ratio =0.223, P =0.003). Conclusion: We herein suggest that the control of bone cement distribution during surgery provides beneficial effects on reducing the risks of recompression after PVP treatment in patients with OVCF.
机译:目的:经皮椎体成形术(PVP)是一种外科手术方法,已广泛用于治疗骨质疏松性椎体压缩性骨折(OVCF)的患者。该过程包括将骨水泥注入骨折的椎骨中。在这项研究中,我们调查了骨水泥在椎体内的分布是否与术后再压缩的发生有关。患者和方法:回顾性分析2008年1月至2013年6月的172例确诊为OVCF的患者。在随访期间,这些患者中有50名在手术后经历了再压缩(再加压组),在随访期间没有观察到122例再加压(对照组)。进行统计分析以比较两组之间的临床和手术参数。结果:再加压组和对照组之间的骨水泥分布存在差异(P = 0.001)。与其他骨水泥分布模式(例如,上终板下方,下终板上方和椎骨中部)相比,在上下端板周围均分布有骨水泥的患者(4/50患者)的再压缩发生率明显更低身体)。逻辑多元回归分析还表明,与分布在椎体中部的骨水泥患者相比,分布在上下端板周围的骨水泥患者的再压缩风险较低(优势比= 0.223,P = 0.003) 。结论:我们在此建议,在手术过程中控制骨水泥分布可为降低OVCF患者PVP治疗后降低再压风险提供有益的效果。

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