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首页> 外文期刊>Clinical kidney journal. >Infliximab as long-term maintenance in steroid-resistant and recurrent sarcoidosis in a renal transplant with central nervous system involvement
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Infliximab as long-term maintenance in steroid-resistant and recurrent sarcoidosis in a renal transplant with central nervous system involvement

机译:英夫利昔单抗作为中枢神经系统受累肾移植中类固醇耐药和复发结节病的长期维持

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Sarcoidosis is a multisystemic, granulomatous disease of unknown aetiology, which commonly involves the lungs, skin and the eyes. Renal sarcoidosis is rare. Recurrent renal sarcoidosis leading to transplant graft failure in adults has not been reported. We report a single case of steroid-resistant sarcoid with recurrence in a renal transplant and the central nervous system that was managed with infliximab. We describe successful resolution of granulomas in the transplant kidney and stabilization of renal function with catastrophic central nervous system recurrence upon withdrawal of infliximab.
机译:结节病是一种病因不明的多系统肉芽肿性疾病,通常涉及肺,皮肤和眼睛。肾结节病罕见。尚未有导致成年人肾移植术后复发的肾结节病复发的报道。我们报告了单例类固醇耐药的类肌瘤,在英夫利昔单抗治疗的肾移植和中枢神经系统中复发。我们描述了英夫利昔单抗撤药后移植肾中肉芽肿的成功解决和具有灾难性中枢神经系统复发的肾功能的稳定。

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