...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Clinical kidney journal. >Warfarin-related nephropathy in a patient with mild IgA nephropathy on dabigatran and aspirin
【24h】

Warfarin-related nephropathy in a patient with mild IgA nephropathy on dabigatran and aspirin

机译：达比加群和阿司匹林对轻度IgA肾病患者的华法林相关肾病

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Dabigatran is a direct thrombin inhibitor used as an alternative to warfarin for long-term anticoagulation. We describe a patient who developed acute kidney injury (AKI) in the setting of warfarin conversion to dabigatran, and a renal biopsy demonstrating acute tubular injury. Although the patient had undiagnosed IgA nephropathy that may have predisposed him to bleeding, AKI was due to heme-associated tubular injury. We propose that severe hematuria in patients with underlying glomerular pathology treated with either dabigatran or warfarin may lead to toxic tubular injury through the accumulation of heme-proteins.
机译：达比加群是一种直接的凝血酶抑制剂，可作为华法林的替代品进行长期抗凝。我们描述了在华法林向达比加群转换的情况下发生急性肾损伤（AKI）的患者，以及显示急性肾小管损伤的肾脏活检。尽管患者未确诊的IgA肾病可能使他易流血，但AKI是由于血红素相关的肾小管损伤所致。我们建议用达比加群或华法林治疗的具有潜在肾小球病变的患者严重血尿可能通过血红素蛋白的积累导致中毒性肾小管损伤。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号