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Presumed levothyroxine-induced pseudotumor cerebri in a pediatric patient being treated for congenital hypothyroidism

机译:在先天性甲状腺功能减退症治疗的儿科患者中推测的左甲状腺素诱发的假性肿瘤脑

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Abstract: Papilledema is considered a neuro-ophthalmic emergency because of its capacity to induce irreversible end-organ damage and the often grave nature of its precipitating factor. Even more concern is warranted when papilledema presents in a pediatric setting. After excluded the contributions of intracranial masses, congenital malformations, ischemic insults and acute infections, the investigation must focus on determining the contributions of other uncharacteristic causes of pediatric pseudotumor cerebri. Pediatric pseudotumor cerebri is a rare clinical entity which shares few commonalities to the adult condition in regards to its predicating factors or symptoms. Without adequate medical history questioning, funduscopic evaluation and ancillary testing, the possibility of an erroneous diagnosis is plausible. This case report aims to disclose the toxic role levothyroxine sodium tablets (Synthroid?, Abbott Laboratories, Abbott Park, IL, USA) played in inducing pseudotumor cerebri in a pediatric patient being treated for congenital hypothyroidism.
机译:【摘要】视乳头状水肿被认为是一种神经性眼科急症,因为它具有引起不可逆的终末器官损害的能力,并且其促发因子通常具有严重的性质。当儿科出现乳头水肿时,甚至需要更多的关注。在排除颅内肿块,先天性畸形,缺血性损伤和急性感染的影响后,研究必须集中在确定小儿伪肿瘤脑的其他非典型原因的影响上。小儿假瘤脑是一种罕见的临床实体,就其预测因素或症状而言,它与成年患者几乎没有共同之处。如果没有足够的病史询问,眼底镜评估和辅助检查,则可能会导致错误诊断。该病例报告旨在揭示左旋甲状腺素钠片(Synthroid ?,雅培实验室,雅培公园,伊利诺伊州,美国)在诱发先天性甲状腺功能减退症的小儿脑中诱发假性肿瘤脑中的毒性作用。

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