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Spontaneous Intestinal Adenocarcinoma in Geriatric Macaques (Macacasp.)

机译：猕猴自发性肠腺癌（Macacasp。）

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BackgroundandPurpose:Intestinaladenocarcinomaappearstobethemostcommonmalignantneoplasminmacaques,andisasubstantialcauseofmorbidityandmortalityintheelderly.brxmlns="http://pub2web.metastore.ingenta.coms/"/brMethods:Aretrospectivereviewof32caseswasdone.brxmlns="http://pub2web.metastore.ingenta.coms/"/brResults:Thirty-twocaseswerereviewed.Clinicalexaminationhadrevealedsevereweightloss,anorexia,andpalpableabdominalmass.Microcytichypochromicanemia,intermittentfecaloccultbloodpositivetestresults,hypoproteinemia,andhypoalbuminemiawerethepredominantclinicallaboratoryfindings.Carcinoembryogenicantigenserologictestingandsingle-strandconformationalpolymorphismanalysiswereperformedinselectedcases.Themostcommonsitesoftheintestinaladenocarcinomawereileocecaljunction,colon,ileum,jejunum,andcecum.Metastaseswereevidentin34%ofthecasesandinvolvedperipheralnodes,liver,lungs,pancreas,andadrenalgland.Overallsurvivalof12macaquesthatunderwentsurgicalexcisionwas83%at6months,58%at1year,50%at1.5years,33%at2years,and8%at4years.Theoverallmeansurvivalrate(MSR)was483postoperativedays.brxmlns="http://pub2web.metastore.ingenta.coms/"/brConclusion:Intestinaladenocarcinomasshouldbeamenabletosurgicalresection.Earlydetectionoflocalized,non-invasiveneoplasmswillincreasesurgicalcurerate.Survivabilitycouldbepotentiallyimprovedbyuseofadjuvanttherapies.
机译：背景与目的：肠上腺癌似乎是猕猴中最常见的恶性新血浆，并且在老年人中有很大的发病率和死亡率。 NS /“> 结果：第三twocaseswerereviewed.Clinicalexaminationhadrevealedsevereweightloss，厌食，andpalpableabdominalmass.Microcytichypochromicanemia，intermittentfecaloccultbloodpositivetestresults，低蛋白血症，andhypoalbuminemiawerethepredominantclinicallaboratoryfindings.Carcinoembryogenicantigenserologictestingandsingle-strandconformationalpolymorphismanalysiswereperformedinselectedcases.Themostcommonsitesoftheintestinaladenocarcinomawereileocecaljunction，结肠，回肠，空肠，andcecum.Metastaseswereevidentin34％ofthecasesandinvolvedperipheralnodes，肝，肺，在手术切除后，12个Macaquesthat的整体生存率在6个月时为83％，1年时为58％，1.5年时为50％。 ，分别在2年时33％和4年时8％。术后平均总生存率（MSR）> 483天。通过使用辅助疗法可能会提高生存能力。

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