Development of Breeding Populations of Rhesus Macaques (Macaca mulatta) That Are Specific Pathogen-free for Rhesus Cytomegalovirus

Barry; Peter A; nbsp; Strelow; Lisa

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Development of Breeding Populations of Rhesus Macaques (Macaca mulatta) That Are Specific Pathogen-free for Rhesus Cytomegalovirus

机译：恒河猴巨细胞病毒无特定病原的恒河猴猕猴（Macaca mulatta）繁殖种群的发展

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Developmentofbreedingcoloniesofrhesusmacaques(Macacamulatta)thatarespecificpathogen-free(SPF)forrhesuscytomegalovirus(RhCMV)isrelativelystraightforwardandrequiresfewmodificationsfromcurrentSPFprograms.InfantsseparatedfromthedamatorwithinafewdaysofbirthandcohousedwithsimilarlytreatedanimalsremainRhCMVseronegativeindefinitely,providedtheyareneverdirectlyorindirectlyexposedtoaRhCMV-infectedmonkey.Bysystematicallycohousingseronegativeanimalsintolargersocialcohorts,breedingpopulationsofanimalsSPFforRhCMVcanbeestablished.TheadditionalcostsinvolvedinexpandingthecurrentdefinitionofSPFstatustoincludeRhCMVareincrementalcomparedwiththemoneyalreadybeingspentonexistingSPFefforts.Moreover,thelargeincreaseinresearchopportunitiesavailableforRhCMV-freeanimalsarguablywouldfarexceedthedevelopmentcosts.PotentialnewareasofresearchandfurtherexpansionofexistingresearcheffortsinvolvingthesenewlydefinedSPFanimalswouldhavedirectimplicationsforimprovementsinhumanhealth.

机译：Developmentofbreedingcoloniesofrhesusmacaques（Macacamulatta）免费thatarespecificpathogen（SPF）forrhesuscytomegalovirus（RhCMV）isrelativelystraightforwardandrequiresfewmodificationsfromcurrentSPFprograms.InfantsseparatedfromthedamatorwithinafewdaysofbirthandcohousedwithsimilarlytreatedanimalsremainRhCMVseronegativeindefinitely，providedtheyareneverdirectlyorindirectlyexposedtoaRhCMV-infectedmonkey.Bysystematicallycohousingseronegativeanimalsintolargersocialcohorts，breedingpopulationsofanimalsSPFforRhCMVcanbeestablished.TheadditionalcostsinvolvedinexpandingthecurrentdefinitionofSPFstatustoincludeRhCMVareincrementalcomparedwiththemoneyalreadybeingspentonexistingSPFefforts.Moreover，thelargeincreaseinresearchopportunitiesavailableforRhCMV-freeanimalsarguablywouldfarexceedthedevelopmentcosts.PotentialnewareasofresearchandfurtherexpansionofexistingresearcheffortsinvolvingthesenewlydefinedSPFanimalswouldhavedirectimplicationsforimprovementsinhumanhealth。

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《Comparative Medicine》 |2008年第1期|共页
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Barry; Peter A; nbsp; Strelow; Lisa;
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中图分类畜牧、动物医学、狩猎、蚕、蜂;
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1. Development of breeding populations of rhesus macaques (Macaca mulatta) that are specific pathogen-free for rhesus cytomegalovirus [J] . Barry Peter A., Strelow Lisa Comparative Medicine . 2008,第1期

机译：恒河猴巨细胞病毒无特定病原体的恒河猴（Macaca mulatta）繁殖种群的发展
2. Genetic characterization of specific pathogen-free rhesus macaque (Macaca Mulatta) populations at the California National Primate Research Center (CNPRC) [J] . Kanthaswamy S., Kou A., Satkoski J., American journal of primatology . 2010,第7期

机译：加利福尼亚国家灵长类动物研究中心（CNPRC）的特定无病原恒河猴（Macaca Mulatta）种群的遗传特征
3. Longitudinal Patterns of Viremia and Oral Shedding of Rhesus Rhadinovirus and Retroperitoneal Fibromatosis Herpesviruses in Age-Structured Captive Breeding Populations of Rhesus Macaques (Macaca mulatta) [J] . White Jessica A., Yang Xiaowei, Todd Patricia A., Comparative Medicine . 2011,第1期

机译：恒河猴猕猴的年龄结构圈养繁殖群中病毒血症的纵向模式和恒河猴鼻病毒和腹膜后纤维增生疱疹病毒的口腔脱落
4. Biomechanics of the Vertebral Column and Internal Organ Response to Seated Spinal Impact in the Rhesus Monkey (Macaca Mulatta) [C] . L. E. Kazarian, J. W. Hahn, H. E. von Gierke Stapp Car Crash Conference . 2009

机译：椎体柱的生物力学和内部器官对岩石猴（Macaca Mulatta）坐着的脊柱冲击的反应
5. Growing Up Rhesus: A Dynamic Systems Approach to Spatial Cognitive Development and Early Experience in Free-Ranging Rhesus Macaques ( Macaca mulatta) [D] . Fleener, Christine E. 2018

机译：恒河猴的成长：一种动态系统方法，用于空间猕猴的空间认知发展和早期经验（猕猴）
6. Development of Breeding Populations of Rhesus Macaques (Macaca mulatta) That Are Specific Pathogen-free for Rhesus Cytomegalovirus [O] . Peter A Barry, Lisa Strelow 2008

机译：恒河猴巨巨病毒无病原的恒河猕猴（Macaca mulatta）繁殖种群的发展
7. SNP-based genetic characterization of the Tulane National Primate Research Center's conventional and specific pathogen-free rhesus macaque (Macaca mulatta ) populations [O] . Sree Kanthaswamy, Jillian Ng, Robert F. Oldt, 2017

机译：基于SNP的Tulane国家灵长类动物研究中心的常规和特异性无病原体绵羊猕猴（Macaca Mulatta）人群的遗传表征

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Development of Breeding Populations of Rhesus Macaques (Macaca mulatta) That Are Specific Pathogen-free for Rhesus Cytomegalovirus

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