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Normal Hematologic and Serum Clinical Chemistry Values for Captive Chimpanzees (Pan troglodytes)

机译:圈养黑猩猩(盘状穴居人)的正常血液学和血清临床化学值

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Inthestudyreportedhere,referenceintervalsforhematologicandserumclinicalchemistryvariablesinthechimpanzee(Pantroglodytes)weredevelopedandcharacterized.Datawerecollectedlongitudinallyacrossa10-yearperiodfor86subjectsatthePrimateFoundationofArizona(PFA).Variablesincludedninestandardhematologicand25standardserumclinicalchemistryvalues.Ananalysisofvariance(ANOVA)wasusedtotestformaineffectsbyageandsex.Inaddition,PFAmeanandrangevalueswerecomparedwiththosepublishedforhumansandsixotherchimpanzeecolonies.TheANOVAresultssuggestanageeffectonhematologic(meancorpuscularhemoglobin,meancorpuscularvolume,neutrophils)andserumclinicalchemical(creatinine,totalprotein,globulin,tryglycerides,directbilirubin,iron,(#59138;-glutamyltransferase,alaninetransaminase,creatinekinase)values.Inaddition,sexhadamaineffectonseveralvariables(redbloodcells,hemoglobinconcentration,hematocrit,uricacidandsodiumconcentrations,andaspartatetransminaseandcreatinekinaseactivities);valuesformalesweregreaterthanthoseforfemales.Further,humanandchimpanzeemeanandrangevaluesoftenwereindistinguishablefromoneanother.However,changesinhumanandchimpanzeevaluesassociatedwithagedifferandsuggestthathematologicandserumclinicalchemistryvaluesmaybedifferentiallyaffectedbyphysicalandsexualmaturationinhumansandchimpanzees.
机译:Inthestudyreportedhere,referenceintervalsforhematologicandserumclinicalchemistryvariablesinthechimpanzee(Pantroglodytes)weredevelopedandcharacterized.Datawerecollectedlongitudinallyacrossa10-yearperiodfor86subjectsatthePrimateFoundationofArizona(PFA).Variablesincludedninestandardhematologicand25standardserumclinicalchemistryvalues.Ananalysisofvariance(ANOVA)wasusedtotestformaineffectsbyageandsex.Inaddition,PFAmeanandrangevalueswerecomparedwiththosepublishedforhumansandsixotherchimpanzeecolonies.TheANOVAresultssuggestanageeffectonhematologic(meancorpuscularhemoglobin,meancorpuscularvolume,中性粒细胞)andserumclinicalchemical(肌酐,总蛋白,球蛋白,甘油三酯,directbilirubin,铁,( #59138;-谷氨酰转移酶,丙氨酸转氨酶,肌酸激酶)值。此外,性骚扰主要影响多种变量(红血球,血红蛋白浓度,血细胞比容,尿酸和钠浓度,天冬氨酸转氨酶和肌酸激酶活性);她和人类的黑猩猩的范围值软性可以彼此区别开来。但是,人类和黑猩猩的值变化与不同的生理和血清临床化学值可能会受到人类和黑猩猩的物理成熟度的不同影响。

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