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首页> 外文期刊>Comparative and functional genomics >Regulation of Translation Initiation under Abiotic Stress Conditions in Plants: Is It a Conserved or Not so Conserved Process among Eukaryotes?
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Regulation of Translation Initiation under Abiotic Stress Conditions in Plants: Is It a Conserved or Not so Conserved Process among Eukaryotes?

机译：植物非生物胁迫条件下翻译起始的调控：真核生物中保守还是保守？

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摘要

For years, the study of gene expression regulation of plants in response to stress conditions has been focused mainly on the analysis of transcriptional changes. However, the knowledge on translational regulation is very scarce in these organisms, despite in plants, as in the rest of the eukaryotes, translational regulation has been proven to play a pivotal role in the response to different stresses. Regulation of protein synthesis under abiotic stress was thought to be a conserved process, since, in general, both the translation factors and the translation process are basically similar in eukaryotes. However, this conservation is not so clear in plants as the knowledge of the mechanisms that control translation is very poor. Indeed, some of the basic regulators of translation initiation, well characterised in other systems, are still to be identified in plants. In this paper we will focus on both the regulation of different initiation factors and the mechanisms that cellular mRNAs use to bypass the translational repression established under abiotic stresses. For this purpose, we will review the knowledge from different eukaryotes but paying special attention to the information that has been recently published in plants.
机译：多年来，对植物响应胁迫条件的基因表达调控的研究主要集中在转录变化的分析上。然而，尽管在植物中，如在真核生物的其余部分中一样，尽管在植物中，关于翻译调控的知识却非常缺乏，事实证明，翻译调控在对不同压力的反应中起关键作用。非生物胁迫下蛋白质合成的调控被认为是一个保守的过程，因为一般而言，真核生物的翻译因子和翻译过程基本相似。但是，这种保护在植物中并不十分清楚，因为控制翻译机制的知识非常匮乏。的确，在其他系统中已充分表征的翻译起始的一些基本调节物仍需在植物中鉴定。在本文中，我们将专注于不同起始因子的调控以及细胞mRNA在非生物胁迫下绕过建立的翻译抑制的机制。为此，我们将回顾来自不同真核生物的知识，但要特别注意植物中最近发表的信息。

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