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Cutaneous B-Cell Lymphoma in a Perdido Key Beach Mouse (Peromyscus poliontus trissyllepsis)

机译:Perdido Key Beach小鼠(Peromyscus poliontus trissyllepsis)的皮肤B细胞淋巴瘤

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ThePerdidoKeybeachmouse(Peromyscuspoliontustrissyllepsis)isanendangeredmammalindigenoustothepanhandlebeachesofNorthwestFlorida.Acaptive3.5-y-oldfemalemousewasevaluatedbecauseofseverepruritus,diffusealopecia,skinreddening,andulcerationsoverthedorsumofherbody.Initialskinbiopsyoftheaffectedareasuggestedbacterialdermatitisbutwasinconclusive.Despiteempiricantibiotic,anthelmintic,andantihistaminetreatments,shecontinuedtodeclineanddevelopedsevereulcerationsoverthemajorityofherbody.Postmortemhistopathologicevaluationledtoatentativediagnosisofepitheliotropiclymphoma,suggestiveofamycosisfungoidesT-cell#8211;typecutaneouslymphoma.However,immunohistochemistryresultschallengedthisdiagnosis,indicatingthatthelesionwasactuallyanepidermotropicB-celllymphoma.SpontaneouscutaneousB-celllymphomasarerareinrodentsandhadnotpreviouslybeenreportedtooccurinPerdidoKeybeachmice.ThiscasereportprovidesinitialevidencethatthePerdidoKeybeachmouseissusceptibletocutaneousB-celllymphoma.
机译:ThePerdidoKeybeachmouse(Peromyscuspoliontustrissyllepsis)isanendangeredmammalindigenoustothepanhandlebeachesofNorthwestFlorida.Acaptive3.5-Y-oldfemalemousewasevaluatedbecauseofseverepruritus,diffusealopecia,skinreddening,andulcerationsoverthedorsumofherbody.Initialskinbiopsyoftheaffectedareasuggestedbacterialdermatitisbutwasinconclusive.Despiteempiricantibiotic,驱虫,andantihistaminetreatments,shecontinuedtodeclineanddevelopedsevereulcerationsoverthemajorityofherbody.Postmortemhistopathologicevaluationledtoatentativediagnosisofepitheliotropiclymphoma,suggestiveofamycosisfungoidesT小区#8211; typecutaneouslymphoma.However,immunohistochemistryresultschallengedthisdiagnosis,indicatingthatthelesionwasactuallyanepidermotropicB-celllymphoma.SpontaneouscutaneousB-细胞淋巴瘤是尖锐的啮齿动物,以前没有报道过发生在PerdidoKeybeach小鼠身上。这种情况提供的初步证据表明,PerdidoKeybeach小鼠对皮肤B细胞淋巴瘤敏感。

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