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Stromal Decidualization of Endometriosis in the Rhesus Macaque (Macaca mulatta): A Case Report

机译:猕猴内膜异位症的间质蜕膜化(一例)

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Duringexploratorylaparotomy,a10-year-oldfemalerhesusmacaquewasfoundtohavea6.0×9.5×2.0-cmmultichambered,yellow,cysticmasscranialtotheuterus,fromwhichlargeamountsofopaque,whitefluidweredischargedintotheabdominalcavity.Theanimalwaseuthanized,andthebodywassubmittedforgrossandhistologicevaluation.Sectionsofthemassexaminedmicroscopicallyconsistedofsheetsofpolygonaltoroundcells,withwelldefinedcellbordersandmoderateamountsofeosinophiliccytoplasm.Scatteredthroughoutthesecellswerefew,variablysizedglandularstructurescomposedofcolumnartocuboidalepithelium.Glandularepithelialcellswerepositiveforkeratin,andthesheetsofpolygonalcellswerepositiveforvimentinandnegativeforkeratinandCD68.Grossandhistologicappearance,immunohistochemicalfindings,andhistoryofmedroxyprogesteroneacetateinjectionswerecompatiblewithadiagnosisofstromaldecidualizationofendometriosis.Subsequentbiopsiesofsimilarlesionsinotherrhesusmacaquesinthecolonybeingtreatedwithmedroxyprogesteroneacetateforendometriosisrevealedcomparablehistologicfindings.
机译:Duringexploratorylaparotomy,A10年oldfemalerhesusmacaquewasfoundtohavea6.0×9.5×2.0 cmmultichambered,黄色,cysticmasscranialtotheuterus,fromwhichlargeamountsofopaque,whitefluidweredischargedintotheabdominalcavity.Theanimalwaseuthanized,andthebodywassubmittedforgrossandhistologicevaluation.Sectionsofthemassexaminedmicroscopicallyconsistedofsheetsofpolygonaltoroundcells,withwelldefinedcellbordersandmoderateamountsofeosinophiliccytoplasm.Scatteredthroughoutthesecellswerefew,variablysizedglandularstructurescomposedofcolumnartocuboidalepithelium.Glandularepithelialcellswerepositiveforkeratin,andthesheetsofpolygonalcellswerepositiveforvimentinandnegativeforkeratinandCD68.Grossandhistologicappearance,immunohistochemicalfindings,andhistoryofmedroxyprogesteroneacetateinjectionswerecompatiblewithadiagnosisofstromaldecidualizationofendometriosis.Subsequentbiopsiesofsimilarlesionsinotherrhesusmacaquesinthecolonybeingtreatedwithmedroxyprogesteroneacetateforendometriosisrevealedcomparablehistolog发现。

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