...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Biology Open >Analysis of the shape fluctuations of reconstituted membranes using GUVs made from lipid extracts of invertebrates
【24h】

Analysis of the shape fluctuations of reconstituted membranes using GUVs made from lipid extracts of invertebrates

机译：用无脊椎动物脂质提取物制成的GUV分析重组膜的形状波动

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Changes in the physical properties of the lipid matrix of cell membranes have repeatedly been proposed to underlie stresses associated with e.g. drought, cold and xenobiotics. Therefore, the ability to experimentally monitor such properties is central to the fundamental physiological understanding of adaptive changes. Here, we test the analysis of shape fluctuations in membranes composed of lipid extracts from two soil invertebrates, and show that theories and experimental approaches previously developed for simpler liposomes may be applied directly to reconstituted membrane lipids. Specifically, we show how the bending rigidity of giant unilamellar liposomes of lipid extracts can be determined precisely. We suggest that future measurements of this parameter could elucidate mechanisms of adaptive processes such as changes in lipid composition and accumulation of protective osmolytes.
机译：细胞膜脂质基质的物理性质的变化已被反复提出来作为与例如脂蛋白相关的应激的基础。干旱，寒冷和异种生物。因此，通过实验监视此类属性的能力对于适应性变化的基本生理理解至关重要。在这里，我们测试了由两种土壤无脊椎动物的脂质提取物组成的膜的形状波动的分析，并表明先前为简单脂质体开发的理论和实验方法可以直接应用于重构的膜脂质。具体来说，我们展示了如何精确确定脂质提取物的单层巨大脂质体的抗弯刚度。我们建议该参数的未来测量可以阐明适应性过程的机制，例如脂质成分的变化和保护性渗透物的积累。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号