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Immunohematological Reference Ranges for Adults from the Central African Republic

机译:中非共和国成年人的免疫血液学参考范围

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A survey was carried out on 150 healthy adults to establish hematological reference ranges for human immunodeficiency virus (HIV)-negative adults from the Central African Republic (CAR). Immunohematological mean values, medians, and 95th-percentile reference ranges were established. Mean values were as follows: leukocyte (WBC) counts, 5.28 × 109/liter (males) and 5.11 × 109/liter (females); erythrocyte counts, 5.20 × 1012/liter (males) and 4.50 × 1012/liter (females); hemoglobin, 15.1 g/dl (males) and 12.5 g/dl (females); hematocrit, 45% (males) and 37% (females); lymphocytes, 2,587/μl (males) and 2,466/μl (females); CD4 T cells, 927/μl (males) and 940/μl (females); CD8 T cells, 898/μl (males) and 716/μl (females); and CD4/CD8 T-cell ratio, 1.13 (males) and 1.41 (females). We concluded that (i) the WBC and hemoglobin values of healthy HIV-negative adults from the CAR are lower than the reference values currently used in the CAR and (ii) the absolute CD4 T-cell counts of healthy HIV-negative adults from the CAR are similar to values for Europeans but the absolute CD8 T-cell counts are much higher. Thus, the CD4/CD8 T-cell ratios for healthy adults from the CAR are significantly reduced compared to the ratios for healthy Europeans.
机译:对150名健康成年人进行了一项调查,以确定来自中非共和国(CAR)的人类免疫缺陷病毒(HIV)阴性成年人的血液学参考范围。建立了免疫血液学平均值,中位数和95%的参考范围。平均值如下:白细胞(WBC)计数,男性为5.28×10 9 /升(女性)和5.11×10 9 /升(女性);红细胞计数:5.20×10 12 /升(男性)和4.50×10 12 /升(女性);血红蛋白:15.1 g / dl(男性)和12.5 g / dl(女性);血细胞比容,45%(男性)和37%(女性);淋巴细胞,2,587 /μl(男性)和2,466 /μl(女性); CD4 T细胞,927 /μl(雄性)和940 /μl(雌性); CD8 T细胞,898 /μl(雄性)和716 /μl(雌性); CD4 / CD8 T细胞比率为1.13(男性)和1.41(女性)。我们得出的结论是:(i)来自CAR的健康HIV阴性成年人的WBC和血红蛋白值低于当前用于CAR的参考值,以及(ii)来自CAR的健康HIV阴性成年人的CD4 T细胞绝对计数。 CAR与欧洲人的值相似,但CD8 T细胞的绝对计数要高得多。因此,与健康欧洲人相比,来自CAR的健康成年人的CD4 / CD8 T细胞比率显着降低。

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