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首页> 外文期刊>Conference Papers in Science >Complete Responses after Hyperthermic Ablation by Ultrasound Guided High Intensity Focused Ultrasound Plus Systemic Chemotherapy for Locally Advanced Pancreatic Cancer
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Complete Responses after Hyperthermic Ablation by Ultrasound Guided High Intensity Focused Ultrasound Plus Systemic Chemotherapy for Locally Advanced Pancreatic Cancer

机译：超声引导高强度聚焦超声加全身化疗对局部晚期胰腺癌的高温消融后的完全反应

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We describe results in unresectable pancreatic tumors treated with USgHIFU hyperthermia ablation plus adjuvant chemotherapy.Materials and Methods. Thirty two cases of nonresectable pancreatic tumors were treated from March 2010 to March 2012, and all of them underwent systemic chemotherapy. Clinical responses (thermal ablation achieved) were measured by image techniques. There were 23 stage III cases and 9 stage IV cases. Complications were also analyzed.Results. Clinical responses (ablation obtained) were 82% in all cases, sustained at 8 weeks of the procedure. We obtained 8 complete responses (25%) at the end of the combined treatment, 7 from stage III patients and 1 from stage IV. Major complications included (1) severe pancreatitis with GI bleeding and (2) skin burning grade III that required plastic surgery. No deaths were registered. Median survival was 12.5 month (6 months–2.5 year).Conclusion. HIFU plus SC is a potentially effective and safe modality for the treatment of unresectable pancreatic cancer.
机译：我们描述了用USgHIFU高温消融加辅助化疗治疗无法切除的胰腺肿瘤的结果。材料和方法。从2010年3月至2012年3月，治疗了32例不可切除的胰腺肿瘤，所有患者均接受了全身化学疗法。通过图像技术测量临床反应（达到热消融）。 III期23例，IV期9例。还分析了并发症。结果。在所有情况下，临床反应（获得消融）均为82％，在手术的8周内持续。在联合治疗结束时，我们获得了8个完全缓解（25％），III期患者为7个，IV期患者为1个。主要并发症包括（1）伴有消化道出血的严重胰腺炎和（2）需要整形手术的III级皮肤灼伤。没有死亡记录。中位生存期为12.5个月（6个月至2.5年）。结论。 HIFU加SC是治疗不可切除的胰腺癌的潜在有效且安全的方法。

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