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首页> 外文期刊>Critical Ultrasound Journal >Changes in speckle-tracking-derived mechanical dispersion index are associated with 30-day readmissions in acute heart failure
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Changes in speckle-tracking-derived mechanical dispersion index are associated with 30-day readmissions in acute heart failure

机译：源自斑点追踪的机械分散指数的变化与急性心力衰竭30天再入院有关

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BackgroundThe objective of the present study was to evaluate the relationship between speckle-tracking-derived parameters left ventricular (LV) mechanical dispersion index (MDI), defined as the standard deviation of the time-to-peak longitudinal strain of all segments analyzed of the LV, and global longitudinal strain (GLS) and 30-day post-discharge outcomes (death and readmission to the hospital) in patients with acute heart failure (AHF). MethodsWe performed a prospective observational study of selected emergency department patients with a primary diagnosis of AHF. Point-of-care echocardiograms were performed at baseline (prior to, or concurrent with the initiation of treatment) and 23?h post-enrollment. Offline speckle-tracking analysis was utilized to calculate GLS and MDI. The primary outcome was 30-day readmissions. ResultsA total of 31 patients were included, 13 of whom were readmitted within 30?days. Patients who were not readmitted to the hospital experienced an average relative improvement in MDI of 24% from baseline to 23?h (84?ms to 64?ms), while patients who were readmitted experienced an average relative worsening in MDI of 6% (66?ms to 70?ms) from baseline to 23?h. ConclusionsMDI has promise as a treatment response variable in admitted patients with AHF; however, further study is needed.
机译：背景本研究的目的是评估散斑跟踪派生参数与左心室（LV）机械弥散指数（MDI）之间的关系，该参数定义为所分析的所有片段的峰时纵向应变的标准偏差。急性心力衰竭（AHF）患者的左心室，总纵向拉力（GLS）和出院后30天的结果（死亡和再次住院）。方法我们对选定的具有AHF初步诊断的急诊科患者进行了一项前瞻性观察研究。现场（在治疗开始之前或与之同时进行）和入选后23小时进行即时超声心动图检查。利用离线斑点跟踪分析来计算GLS和MDI。主要结果是入院30天。结果共纳入31例患者，其中13例在30天之内再次入院。未重新入院的患者的MDI从基线到23？h（从84？ms到64？ms）的平均相对改善为24％，而重新入院的患者的MDI的平均相对恶化为6％（从基线到23？h为66？ms至70？ms）。结论：MDI有望作为AHF入院患者的治疗反应变量。但是，还需要进一步研究。

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