• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Acta medica (Hradec Kralove) / >Histological Features of Oral Cavity Mucous Membrane Epithelium in Six-Month-Old Experimental Animals Born with Macrosomia
【24h】

Histological Features of Oral Cavity Mucous Membrane Epithelium in Six-Month-Old Experimental Animals Born with Macrosomia

机译：出生六个月大的大儿实验动物口腔黏膜膜上皮的组织学特征

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We examined the histological features of the mucobuccal fold of oral cavity mucous membrane from the area of the masticatory teeth roots’ projection in 6-month-old Wistar Albino Glaxo rats with fetal macrosomia. The animals were divided into groups according to the body weight, the body length, and the Quetelet index at birth. A morphological study was performed using the Leica SP8 AOBS laser scanning confocal microscope and a conventional light (Axiostar, Zeiss) microscopy. Morphometric parameters were used to estimate the degree of acanthosis development in the epithelium of the oral mucosa, which indicates the intensity of its proliferation. Numerous narrow and deep acanthotic outgrowths and densely located ‘juvenile’ epitheliocytes in the basal layer on the apex of the acanthotic protrusions were found in animals with fetal macrosomia that was due to intrauterine obesity. In these animals, the morphometric index, which we used, was maximally different from that in the control group. In animals with fetal macrosomia that was due to intrauterine growth acceleration of the body, the hyperproliferation of the mucous membrane epithelium of the oral cavity was absent or little pronounced. It can be assumed that fetal macrocosmia with obesity causes instability in the epithelium of the oral cavity mucosa, its rapid death, and therefore, a more active stimulation of proliferation.
机译：我们从6个月大的Wistar Albino Glaxo胎儿巨眼症患者的咀嚼齿根突起区域检查了口腔黏膜粘膜颊粘膜褶皱的组织学特征。根据出生时的体重，体长和克托莱特指数将动物分为几组。使用Leica SP8 AOBS激光扫描共聚焦显微镜和常规光镜（Axiostar，Zeiss）进行了形态学研究。使用形态学参数估计口腔粘膜上皮中棘皮症的发展程度，这表明其增殖的强度。在由于胎儿宫内肥胖而引起的胎儿巨大儿的动物中，发现了许多狭窄而深的棘生性产物以及在棘生性突起顶点的基底层中密集分布的“幼稚”上皮细胞。在这些动物中，我们使用的形态计量指数与对照组最大不同。在由于胎儿的子宫内生长加速而导致胎儿巨大儿的动物中，口腔粘膜上皮的过度增生不存在或几乎没有明显表现。可以认为，肥胖的胎儿大世界症引起口腔粘膜上皮的不稳定性，其迅速死亡，并因此更积极地刺激增殖。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号