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Assessment of pyridoxine and folate intake in migraine patients

机译:偏头痛患者吡ido醇和叶酸摄入量的评估

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Background: Migraine is a highly prevalent disorder worldwide. It affects 10–20% of the population during their lifetime. Recent studies have indicated that supplementation with folate and pyridoxine improves migraine symptoms. This study was undertaken to evaluate dietary intake of folate and pyridoxine in migraine patients and assessed their association with the frequency of migraine attacks. Materials and Methods: This is a case–control study performed on 124 migraine patients and 130 non-migraine subjects. Individuals' common dietary intake was determined by using a valid semi-quantitative 168-item food frequency questionnaire (FFQ). Data had been analyzed using independent t -test using SPSS software (version 18). Results: In this study, we found that migraine patients had lower intake of dietary folate compared with control group, but energy and pyridoxine intake were not different between the two groups. Further analysis among men and women revealed no statistically significant changes in these relationships. In addition, we found no significant association between dietary intake of pyridoxine and folate with the frequency of migraine attacks. Conclusion: Migraine patients had lower dietary intake of folate, compared with non-migraine group subjects. There was no significant association between folate and pyridoxine intake with the frequency of migraine attacks. Further studies are needed to confirm our findings.
机译:背景:偏头痛是世界范围内高度流行的疾病。在其一生中,它影响着10%至20%的人口。最近的研究表明,补充叶酸和吡ido醇可改善偏头痛症状。这项研究旨在评估偏头痛患者的饮食中叶酸和吡ido醇的摄入量,并评估它们与偏头痛发作频率的关系。材料和方法:这是一项对124位偏头痛患者和130位非偏头痛患者进行的病例对照研究。通过使用有效的半定量168项食物频率问卷(FFQ)确定个人的日常饮食摄入量。数据已使用SPSS软件(版本18)通过独立的t检验进行了分析。结果:在这项研究中,我们发现偏头痛患者的饮食中叶酸的摄入量低于对照组,但两组的能量和吡ido醇摄入量没有差异。男女之间的进一步分析表明,这些关系没有统计学上的显着变化。此外,我们发现饮食中吡ido醇和叶酸的摄入与偏头痛发作的频率之间没有显着相关性。结论:与非偏头痛组受试者相比,偏头痛患者的饮食中叶酸的摄入量较低。叶酸和吡ido醇的摄入与偏头痛发作的频率之间没有显着相关性。需要进一步研究以确认我们的发现。

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