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首页> 外文期刊>Acta Radiologica Open >Acoustic radiation force impulse (ARFI) shear wave elastography of the bowel wall in healthy volunteers and in ulcerative colitis
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Acoustic radiation force impulse (ARFI) shear wave elastography of the bowel wall in healthy volunteers and in ulcerative colitis

机译:健康志愿者和溃疡性结肠炎肠壁的声辐射力脉冲(ARFI)剪切波弹性成像

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Background Acoustic radiation force impulse (ARFI) elastography is a non-invasive, ultrasound-based approach of evaluation of tissue elasticity. It has not yet been systematically applied to the bowel wall. Purpose To perform ARFI elastography of the bowel wall in healthy volunteers and patients with ulcerative colitis (UC). Material and Methods A high-frequency ultrasound (with bowel wall thickness and vascularization score) and an ARFI elastography of the bowel wall were performed in 20 patients with UC and 13 healthy volunteers. At least 10 ARFI measurements were obtained within the terminal ileum and the ascending, transverse, descending, and sigmoid colon and correlated with results of high-frequency ultrasound. Results The UC group had mostly moderate disease activity. All patients had signs of inflammation upon B-mode ultrasound. Eight patients showed an ulcerative (ileo)pancolitis. Overall, ARFI elastography values and wall thickness were higher in the UC group than in the group of healthy volunteers (P?=?0.021 and P??0.001, respectively). ARFI velocities of the separate segments were significantly higher in the transverse (P?=?0.045) and sigmoid colon (P?=?0.032) in case of UC. Conclusion ARFI elastography of the bowel wall of the colonic frame and the terminal ileum is feasible but shows high standard deviation. ARFI shear wave velocities appear to be slightly higher in patients with UC than in healthy volunteers, particularly in the sigmoid and transverse colon. Further studies are needed.
机译:背景技术声辐射力脉冲(ARFI)弹性成像是一种非侵入性的,基于超声的组织弹性评估方法。它尚未被系统地应用于肠壁。目的对健康志愿者和溃疡性结肠炎(UC)患者进行肠壁的ARFI弹性成像。材料和方法对20例UC患者和13名健康志愿者进行了高频超声检查(具有肠壁厚度和血管化评分)和ARFI肠壁弹性成像。在回肠末端,升结肠,横结肠,降结肠和乙状结肠内至少进行了10次ARFI测量,并与高频超声结果相关。结果UC组的疾病活动主要为中度。所有患者在B型超声检查后都有炎症迹象。八名患者出现溃疡性(回肠)性胰腺炎。总体而言,UC组的ARFI弹性成像值和壁厚均高于健康志愿者组(分别为P <= 0.021和P 0.001)。在UC的情况下,横切面(Pα=?0.045)和乙状结肠(P?=?0.032)的独立节段的ARFI速度明显更高。结论结肠镜架肠壁和回肠末端的ARFI弹性成像是可行的,但标准偏差较高。 UC患者的ARFI剪切波速度似乎比健康志愿者略高,特别是在乙状结肠和横结肠。需要进一步研究。

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