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Association of polymorphisms in the Pit-1 intron 5 with body measurements in Chinese Cattle

机译:Pit-1内含子5中的多态性与中国牛体形的关联

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The?Pit-1?gene was studied as a candidate for genetic markers of growth traits in Chinese cattle in this study. The single-strand conformation polymorphism method was used to identify polymorphism in the?Pit-1?intron 5. One single nucleotide polymorphism,?Pit1I5, was found in intron 5. The frequencies of allele A of Nanyang cattle (NY), Qinchuan cattle (QC), Jiaxianhong cattle (JX), Luxi cattle (LX) and Holstein cow (H) populations were 0.444, 0.477, 0.538, 0.523 and 0.475, respectively. Associations of the polymorphisms with growth traits in Nanyang cattle were analyzed using a general linear model procedure. The following parameters were greater in individuals with AA genotype than with AB genotype: body weight, average day gain, body height, chest girth at six, 12, 18 and 24 months?(P allele B in other age groups. Therefore, genotype AA maybe a dominant genotype and allele A may be a dominant allele. These results imply that allele A of?Pit-1?gene may likely affect growth traits positively.
机译:在本研究中,研究了Pit-1β基因作为中国牛生长性状遗传标记的候选者。用单链构象多态性鉴定Pit-1内含子5的多态性。在内含子5中发现一个单核苷酸多态性,Pit1I5。南阳牛,秦川牛等位基因A的频率(QC),嘉贤红牛(JX),Lux西牛(LX)和荷斯坦奶牛(H)的种群分别为0.444、0.477、0.538、0.523和0.475。使用常规线性模型程序分析了南阳牛的多态性与生长性状的关联。 AA基因型个体的以下参数比AB基因型个体更大:体重,平均日增重,身高,6、12、18和24个月时的胸围?(其他年龄段的P等位基因B。因此,AA基因型这些结果表明,Pit-1β基因的等位基因A可能对生长性状产生积极影响。

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