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首页> 外文期刊>African Journal of Biotechnology >Protective effects of some fruit juices with low-fat diet on rat testis damaged by carbon tetrachloride: A genetic and histological study
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Protective effects of some fruit juices with low-fat diet on rat testis damaged by carbon tetrachloride: A genetic and histological study

机译：一些低脂饮食果汁对四氯化碳损伤大鼠睾丸的保护作用：遗传和组织学研究

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Oxidative stress, free radical, lipid peroxidation and antioxidant have become a common expression with most disease and methods for protection. Carbon tetrachloride (CCl4) is an industrial solvent which has destructive effects on a cell while most fruit juices have antioxidant effects. The aim of this study was to investigate the protective role of fruit juice on testis after toxic effect with CCl4 through oxidative stress with basal diet and low-fat diet. Seventy-five male albino rats were used for this study in which the juices of three fresh fruit, yellow apples (Malus domestica, L.), red grapes containing seeds (Vitis vinifera, L.) and pomegranates (Punica granatum, L.) were used as therapeutic agents. Histological sections of testis indicated that low-fat diet has obvious effects than basal diet in both the low-fat diet with CCl4 "LdC""con++", LdC with grape juice 2 ml "grpL2", LdC with pomegranate juice 2 ml "pomL2" and hyper effect in LdC with pomegranate juice 4 ml "pomL4" while it was equal in effect with basal diet in the other treatments. Low-fat diet gave significant effects (about 75% recovery in con++, LdC with Apple juice 2 ml? and 4 ml "appL2, appL4" , LdC with grape juice 4 ml "grpL4" and pomL2) while 25% began to recover as shown in basal diet with pomegranate juice 4 ml "pomB4" and grpL2. Treatment of rats with pomegranate juice ameliorated the toxic effects of CCl4 with low-fat diet on Semi-random RAPD-DNA profile. Low-fat diet with fruit juice had positive effect against toxicity induced by CCl4 in testes of rats on the level of histological and DNA-RAPD studies.
机译：氧化应激，自由基，脂质过氧化和抗氧化剂已成为大多数疾病和保护方法的常用表达。四氯化碳（CCl4）是一种工业溶剂，对细胞具有破坏性作用，而大多数果汁具有抗氧化作用。这项研究的目的是研究通过基础饮食和低脂饮食的氧化应激，果汁对四氯化碳的毒性作用后对睾丸的保护作用。该研究使用了75只雄性白化病大鼠，其中包括三种新鲜水果，黄色苹果（Malus domestica，L。），含有种子（Vitis vinifera，L。）和石榴（Punica granatum，L。）的红葡萄的汁液。被用作治疗剂。睾丸的组织学切片显示，低脂饮食在含CCl4“ LdC”“ con ++”的低脂饮食，LdC和葡萄汁2 ml“ grpL2”的低脂饮食，LdC和石榴汁2 ml“ pomL2”的低脂饮食中均具有比基础饮食明显的作用。 ”和“石榴汁4 ml pomL4”在LdC中的超效作用，而在其他治疗中，其与基础饮食的作用相当。低脂饮食具有显着效果（使用苹果汁2 ml？和4 ml“ appL2，appL4”的con ++，LdC的回收率约为75％，使用葡萄汁4 ml“ grpL4”和pomL2的LdC的回收率约为25％）在基础饮食中显示有4毫升石榴汁“ pomB4”和grpL2。用石榴汁治疗大鼠，低脂饮食改善了CCl4对半随机RAPD-DNA谱的毒性作用。在组织学和DNA-RAPD研究水平上，低脂饮食加果汁对CCl4诱导的大鼠睾丸毒性具有积极作用。

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