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首页> 外文期刊>African Journal of Biotechnology >The efficacy of seven ethnobotanicals in the treatment of skin infections in Ibadan, Nigeria
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The efficacy of seven ethnobotanicals in the treatment of skin infections in Ibadan, Nigeria

机译：尼日利亚伊巴丹的七种植物药治疗皮肤感染的功效

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In southwestern Nigeria, ethnobotanical investigation confirmed that?Afzelia africana, Alstonia boonei, Azadirachta indica,?Ficus exasperata,?Senna alata,?Tetrapleura tetraptera?and?Xylopia aethiopica?are commonly used in the treatment of skin infections. Therefore, this study examined the?in vitro?antimicrobial activity of crude methanol extracts of the ethnobotanicals against clinical isolates of?Candida albicans, Staphylococcus?aureus?and?Streptococcus pyogenes?associated with skin infections. The isolates (1×10-1 _?1×10-6?cfu/ml) were tested against plant extracts (500 mg/ml) using agar-well diffusion method. The Minimum Inhibitory Concentration (MIC) was determined using broth dilution method. At 10-4?cfu/ml inoculum concentration,?C. albicans?was significantly susceptible (P≤0.05) to methanol extracts of?S. alata?and?X. aethiopica?with 25.0 mm zone of inhibition, while?T. tetraptera?was the most active onS. aureus?with 21.5 mm and?S. pyogenes?was significantly susceptible to?A. africana,A. boonei,?S. alata?and?T. tetraptera?with 25.0 mm zone of inhibition. The significant antimicrobial activities exhibited by the methanol extracts of the ethnobotanicals confirmed their therapeutic potentials in the treatment of skin infections. Also soap, cream and ointment could be prepared from these ethnobotanicals for topical application in the treatment of skin infections. However, their toxicity tests will ascertain safety in administration.
机译：在尼日利亚西南部，民族植物学研究证实，非洲A非洲种，爱沙尼亚布尼，印度印za，无花果榕，番泻叶，四叶藜，四倍体木犀科通常用于治疗皮肤感染。因此，本研究研究了民族植物药粗甲醇提取物对与皮肤感染有关的白色念珠菌，金黄色葡萄球菌和化脓性链球菌临床分离株的体外抗菌活性。使用琼脂井扩散法，针对植物提取物（500mg / ml）测试分离物（1×10-1_α1×10-6αcfu/ ml）。使用肉汤稀释法确定最小抑制浓度（MIC）。接种浓度为10-4？cfu / ml。白色念珠菌对？S的甲醇提取物非常敏感（P≤0.05）。阿拉塔和X。 aethiopica？具有25.0 mm的抑制区，而？T。 tetraptera是最活跃的onS。金黄色的21.5毫米和？化脓性肝炎很容易感染。非洲人布尼，？阿拉塔和T.具25.0毫米抑制区的四足动物。种族植物药的甲醇提取物显示出显着的抗菌活性，证实了它们在治疗皮肤感染中的治疗潜力。也可以从这些民族植物药中制备肥皂，乳脂和药膏，用于局部治疗皮肤感染。但是，它们的毒性测试将确定给药的安全性。

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