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首页> 外文期刊>African Journal of Cellular Pathology >Plasma urea and electrolytes profile in different stages of hiv infection in Ekpoma, Nigeria
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Plasma urea and electrolytes profile in different stages of hiv infection in Ekpoma, Nigeria

机译：尼日利亚埃克波马艾滋病毒感染不同阶段的血浆尿素和电解质分布

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Aim: Human Immune Deficiency Virus (HIV) is one of most dreaded diseases today. This study aims at the determination of electrolyte profile (Na+ , K+ , Cland HCO3 - ), urea levels and CD4 count of patients diagnosed with HIV infection in Ekpoma, Nigeria.Methods: Sixty patients and 40 apparently healthy individuals as controls were examined from January 2013- September 2014. Electrolytes were assayed using flame photometry and titration method for Na+ , K+ , Cl- and HCO3 - respectively. Urea was determined using Urease-berthlot method and CD4 count by partec cyflow counter.Results: The mean values of K+ ; 3.59±0.43, Na+ ; 133.48±3.79, HCO3 - ; 23.44±3.78, and CD4 count; 502.77±317.74 were decreased and showed a significant difference (p0.05) when compared to the control; 20.87±6.49 while that of Cl; 100.08±1.93 was decreased but showed no statistical significant difference (p>0.05) when compared to the control; 100.55±2.01.Conclusion: This study has shown that decreased K+ , Na+ , Cl, HCO3 - , CD4 count and raised urea level may be a valuable index in the diagnosis and monitoring of HIV infected patients.Keywords: Serum urea, Electrolytes, HIV, Infection.
机译：目的：人类免疫缺陷病毒（HIV）是当今最可怕的疾病之一。这项研究旨在确定尼日利亚埃克波马（Ekpoma）确诊为HIV感染患者的电解质分布（Na +，K +，Cland HCO3--），尿素水平和CD4计数。方法：自1月起对60例患者和40例看起来健康的个体进行了检查2013-2014年9月。使用火焰光度法和滴定法分别测定了Na +，K +，Cl-和HCO3-的电解质。用尿素酶联尿法测定尿素​​，用Partic cyflow计数器测定CD4。 3.59±0.43，钠+; 133.48±3.79，HCO 3-; 23.44±3.78，CD4计数;与对照组相比，降低了502.77±317.74，并显示出显着性差异（p0.05）。 Cl为20.87±6.49与对照组相比，降低了100.08±1.93，但无统计学差异（p> 0.05）; 100.55±2.01。结论：这项研究表明，K +，Na +，Cl，HCO3-，CD4计数降低和尿素水平升高可能是诊断和监测HIV感染者的重要指标。关键词：血清尿素，电解质，HIV ， 感染。

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