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Epidemiology of traumatic brain injury patients at Kilimanjaro Christian medical centre, Moshi, Tanzania

机译:坦桑尼亚莫西乞力马扎罗山基督教医学中心的颅脑外伤患者的流行病学

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Introduction Traumatic brain injury (TBI) affects 10 million people annually. Clinical epidemiology can inform prevention initiatives to curb this burden. Kilimanjaro Christian Medical Centre (KCMC) is a referral hospital for 11 million people with neurosurgical capacity located in Moshi, Tanzania. Methods Secondary analysis of a prospective observational TBI Acute Care Registry at the KCMC Casualty Department (CD) included all patients presenting between May 5 and July 27th, 2013. Means with standard deviations (SD), Fisher’s exact or Chi-squared with a binomial logistic regression reporting Odds Ratios (OR) with 95% confidence intervals (CI) was calculated using Stata IC (College Station, TX). Results 171 total patients were enrolled in the TBI Registry. The mean age was 32.1 years (range 1–99, SD 16.6), with 71% between 15 and 45 years of age. 82% were male and 28% cases involved alcohol. Causes of TBI were road traffic injuries (RTI) (74%), assaults (13%) or falls (8%). 52% of RTI’s involved motorcycle users. The mean Glasgow Coma Score (GCS) was 12.6 (range 3-15, SD 4.04) with 19% of patients having severe TBI (GCS of 9). The overall mortality rate was 13% for all CD patients, 14% for admitted patients and 80% for patients admitted to the ICU. Death was associated with hypoxia (OR 16.0 (95% CI 5.4, 47.5), hypotension (OR 7.3 (95% CI 1.4, 38.4) and low GCS (GCS 9, OR 29.7 (95% CI 9.6, 92.0). Severe TBI had a 53% mortality rate, while moderate and mild TBI 12% and 3% fatality rates respectively. Of severe TBI patients, 63.6% suffered disability from their injury compared to 27% of moderate and 3% of mild TBI. Conclusion Most TBI patients were young males involved in road traffic collisions, predominantly involving motorcycles. Over a quarter of them involve alcohol. Our data support that TBI causes significant death and disability.
机译:简介颅脑外伤(TBI)每年影响1000万人。临床流行病学可以为预防措施提供信息,以减轻这种负担。乞力马扎罗山基督教医学中心(KCMC)是一家转诊医院,位于坦桑尼亚莫希,拥有1100万人的神经外科手术能力。方法对KCMC伤亡部(CD)进行的前瞻性观察性TBI急性护理注册中心进行的二级分析包括2013年5月5日至7月27日之间就诊的所有患者。均方差为标准差(SD),Fisher精确度或卡方与二项式对数逻辑使用Stata IC(College Station,TX)计算具有95%置信区间(CI)的回归报告几率(OR)。结果共有171名患者参加了TBI注册表。平均年龄为32.1岁(范围1–99,SD 16.6),其中15%至45岁之间为71%。男性为82%,酒精为28%。 TBI的原因是道路交通伤害(RTI)(74%),攻击(13%)或跌倒(8%)。 RTI有52%的摩托车使用者。格拉斯哥昏迷平均评分(GCS)为12.6(范围3-15,SD 4.04),其中19%的患者患有严重的TBI(GCS <9)。所有CD患者的总死亡率为13%,入院患者为14%,ICU患者为80%。死亡与低氧(OR 16.0(95%CI 5.4,47.5),低血压(OR 7.3(95%CI 1.4,38.4))和低GCS(GCS <9,OR 29.7(95%CI 9.6,92.0)有关。死亡率为53%,中度和轻度TBI分别为12%和3%的死亡率;重度TBI患者中,有63.6%的人因伤致残,而中度和轻度TBI则为27%。是参与道路交通冲突的年轻男性,主要是摩托车,其中四分之一以上是酒精,我们的数据支持TBI会导致严重的死亡和残疾。

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